Adipose tissue has long been identified as the major site of vitamin D storage. Recent
studies have demonstrated that VDR and vitamin D metabolizing enzymes are expressed in …

Observational studies classically find an inverse relationship between human plasma 25-
hydroxyvitamin D concentration and obesity. However, interventional and genetic studies …

Vitamin D receptor (VDR) mediates many genomic and non-genomic effects of vitamin D.
Recently, the mitochondrial effects of vitamin D have been characterized in many cell types …

Obesity is increasing in an alarming rate worldwide, which causes higher risks of some
diseases, such as type 2 diabetes, cardiovascular diseases, and cancer. Current therapeutic …

Human studies have provided relatively strong associations of poor vitamin D status with
Type 2 diabetes but do not explain the nature of the association. Here, we explored the …

The present study aimed to investigate the effects of vitamin D3 (Vit D) administration on
memory function, hippocampal level of amyloid-beta (Aβ), brain-derived neurotrophic factor …

Vitamin D insufficiency is associated with obesity and its related metabolic diseases.
Adipose tissues store and metabolize vitamin D and expression levels of vitamin D …

Objectives Peroxisome proliferator-activated receptor (PPAR) and vitamin D signaling
pathways regulate a multitude of genes involved in different physiological functions. The aim …

Background: In recent years, there has been a growing body of evidence indicating that
replacing cholecalciferol (vitamin D 3) with 25-hydroxycholecalciferol [25 (OH) D 3] through …

Vitamin D, a secosteroid predominately obtained by endogenous production, has in recent
years been linked to obesity and its comorbidities. The purpose of this review is to draw …