Chalcones are a class of privileged scaffolds with high medicinal significance due to the
presence of an α, β-unsaturated ketone functionality. Numerous functional modifications of …

The increased resistance of microorganisms to antimicrobial drugs makes it necessary to
search for new active compounds, such as chalcones. Their simple chemical structure …

The rise of drug‐resistant microbes necessitates the development of new antimicrobial
agents. Increasing resistance among multidrug‐resistant microbes has spurred research …

The pursuit of novel or modified substances based on a natural origin, like flavonoids, is
essential in addressing the increasing number of diseases and bacterial resistance to …

The present work focuses on the synthesis and preliminary structure activity relationships
(SARs) of furan-derived chalcones and their corresponding∆ 2-pyrazoline derivatives as …

Plants are known to have numerous phytochemicals and other secondary metabolites with
numerous pharmacological and biological properties. Among the various compounds …

Porphyromonas gingivalis is crucial for the pathogenesis of periodontitis. This research
investigated the effects of the fruit-derived flavonoid phloretin and its analogs on the growth …

Objective Antibiotic resistance poses a considerable worldwide concern, particularly in
clinical environments where drug-resistant Gram-negative bacteria like Klebsiella …

The newly synthesized fluorinated chalcone derivatives are observed to possess antioxidant
potential. Two new fluorinated chalcone compounds were effectively synthesized using the …

The escalating threat of drug-resistant microbes underscores the urgent need for novel
antimicrobial agents. In response, considerable research effort has been directed towards …