Molecular photoswitches in aqueous environments

J Volarić, W Szymanski, NA Simeth… - Chemical Society …, 2021 - pubs.rsc.org
Molecular photoswitches enable dynamic control of processes with high spatiotemporal
precision, using light as external stimulus, and hence are ideal tools for different research …

Noncovalent interactions in proteins and nucleic acids: Beyond hydrogen bonding and π-stacking

S Jena, J Dutta, KD Tulsiyan, AK Sahu… - Chemical Society …, 2022 - pubs.rsc.org
Understanding the noncovalent interactions (NCIs) among the residues of proteins and
nucleic acids, and between drugs and proteins/nucleic acids, etc., has extraordinary …

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

AE Tron, MA Belmonte, A Adam, BM Aquila… - Nature …, 2018 - nature.com
Mcl-1 is a member of the Bcl-2 family of proteins that promotes cell survival by preventing
induction of apoptosis in many cancers. High expression of Mcl-1 causes tumorigenesis and …

Catalysis of organic reactions through halogen bonding

RL Sutar, SM Huber - ACS Catalysis, 2019 - ACS Publications
Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents,
features very interesting properties, as illustrated by numerous applications continuously …

Halogenated antimicrobial agents to combat drug-resistant pathogens

OS Faleye, BR Boya, JH Lee, I Choi, J Lee… - Pharmacological …, 2024 - Elsevier
Antimicrobial resistance presents us with a potential global crisis as it undermines the
abilities of conventional antibiotics to combat pathogenic microbes. The history of …

[PDF][PDF] Halogen bonds, chalcogen bonds, pnictogen bonds, tetrel bonds and other σ-hole interactions: A snapshot of current progress

L Brammer, A Peuronen… - … Section C: Structural …, 2023 - journals.iucr.org
We report here on the status of research on halogen bonds and other σ-hole interactions
involving p-block elements in Lewis acidic roles, such as chalcogen bonds, pnictogen bonds …

Metal Centers as Nucleophiles: Oxymoron of Halogen Bond‐Involving Crystal Engineering

DM Ivanov, NA Bokach… - … –A European Journal, 2022 - Wiley Online Library
This review highlights recent studies discovering unconventional halogen bonding (HaB)
that involves positively charged metal centers. These centers provide their filled d‐orbitals …

Halogen bonding for molecular recognition: New developments in materials and biological sciences

G Berger, P Frangville, F Meyer - Chemical communications, 2020 - pubs.rsc.org
Two decades ago, halogen bonding attracted considerable attention as a new type of non-
covalent interaction and has now emerged as an important supramolecular tool for crystal …

Halogens in protein–ligand binding mechanism: a structural perspective

NK Shinada, AG de Brevern… - Journal of medicinal …, 2019 - ACS Publications
Halogen atoms have been at the center of many rational medicinal chemistry applications in
drug design. While fluorine and chlorine atoms are often added to enhance physicochemical …

Halogen‐Bonded Organic Framework (XOF) Based on Iodonium‐Bridged N⋅⋅⋅I+⋅⋅⋅N Interactions: A Type of Diphase Periodic Organic Network

G Gong, S Lv, J Han, F Xie, Q Li, N Xia… - Angewandte …, 2021 - Wiley Online Library
Due to the fascinating structures and wide applications, porous materials with open
frameworks have attracted more and more attentions. Herein, a novel two‐dimensional (2D) …