Cdks, cyclins and CKIs: roles beyond cell cycle regulation
S Lim, P Kaldis - Development, 2013 - journals.biologists.com
Cyclin-dependent kinases (Cdks) are serine/threonine kinases and their catalytic activities
are modulated by interactions with cyclins and Cdk inhibitors (CKIs). Close cooperation …
are modulated by interactions with cyclins and Cdk inhibitors (CKIs). Close cooperation …
Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast
DJ Lew, V Dulić, SI Reed - Cell, 1991 - cell.com
We have isolated a number of cDNAs derived from human mRNAs that are able to substitute
for Gl cyclin genes in S. cerevisiae. Several of these encode human cyclins A, Bl, and 82 …
for Gl cyclin genes in S. cerevisiae. Several of these encode human cyclins A, Bl, and 82 …
A family of cyclin homologs that control the G1 phase in yeast.
JA Hadwiger, C Wittenberg… - Proceedings of the …, 1989 - National Acad Sciences
Two Saccharomyces cerevisiae genes were isolated based upon their dosage-dependent
rescue of a temperature-sensitive mutation of the gene CDC28, which encodes a protein …
rescue of a temperature-sensitive mutation of the gene CDC28, which encodes a protein …
Protein kinase activity associated with the product of the yeast cell division cycle gene CDC28.
SI Reed, JA Hadwiger… - Proceedings of the …, 1985 - National Acad Sciences
Antibodies raised against the protein encoded by a lacZ-CDC28 in-frame fusion were shown
to immunoprecipitate the CDC28 product from yeast cell lysates. The polypeptide …
to immunoprecipitate the CDC28 product from yeast cell lysates. The polypeptide …
A cell cycle checkpoint monitors cell morphogenesis in budding yeast.
DJ Lew, SI Reed - The Journal of cell biology, 1995 - rupress.org
Checkpoint controls are regulatory pathways that inhibit cell cycle progression in cells that
have not faithfully completed a prior step in the cell cycle. In the budding yeast …
have not faithfully completed a prior step in the cell cycle. In the budding yeast …
A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Eg1.
SJ Elledge, MR Spottswood - The EMBO journal, 1991 - embopress.org
The onset of S‐phase and M‐phase in both Schizosaccharomyces pombe and
Saccharomyces cerevisiae requires the function of the cdc2/CDC28 gene product, p34, a …
Saccharomyces cerevisiae requires the function of the cdc2/CDC28 gene product, p34, a …
Primary structure homology between the product of yeast cell division control gene CDC28 and vertebrate oncogenes
AT Lörincz, SI Reed - Nature, 1984 - nature.com
In the budding yeast, Saccharomyces cerevisiae, division is controlled in response to
nutrient limitation1 and in preparation for conjugation2. Cells deprived of an essential …
nutrient limitation1 and in preparation for conjugation2. Cells deprived of an essential …
Cdc28 tyrosine phosphorylation and the morphogenesis checkpoint in budding yeast.
A morphogenesis checkpoint in budding yeast delays nuclear division (and subsequent cell
cycle progression) in cells that have failed to make a bud. We show that the ability of this …
cycle progression) in cells that have failed to make a bud. We show that the ability of this …
The Saccharomyces cerevisiae CKS1 gene, a homolog of the Schizosaccharomyces pombe suc1+ gene, encodes a subunit of the Cdc28 protein kinase complex
JA Hadwiger, C Wittenberg… - … and cellular biology, 1989 - Am Soc Microbiol
The Saccharomyces cerevisiae gene CDC28 encodes a protein kinase required for cell
cycle initiation. In an attempt to identify genes encoding proteins that interact with the Cdc28 …
cycle initiation. In an attempt to identify genes encoding proteins that interact with the Cdc28 …