With the increasing number of cases of inactive and drug-resistance tuberculosis, there is an
urgent need to develop new potent molecules set for fighting this brutal disease. Medicinal …

Tuberculosis (TB) has been considered as the highly chronic, contagious and infectious
disorder caused by Mycobacterium tuberculosis (Mtb). Every year more than 10 million …

A series of thiomorpholine and cinnamyl alcohol derivatives, conjugated with cinnamic acid-
containing moieties, such as ferulic acid, sinapic acid and 3, 4-dimethoxycinnamic acid …

A series of Sulfonamide-based Schiff bases (E)-4-(benzylideneamino)-N-(6-
methoxypyridazin-3-yl) benzenesulfonamide (3a-r) targeting Urease Inhibition was …

In this elucidation, we used the available picric acid commercial for the synthesis of different
heterocyclics such as carbothioamide and 1, 3, 4-oxadiazole and different Schiff bases …

Urease is an attractive drug target for designing anti-infective agents against pathogens
such as Helicobacter pylori, Proteus mirabilis, and Ureaplasma urealyticum. In the past …

This study reports the synthesis and biological investigation of three series of novel
monocyclic β-lactam derivatives bearing a morpholine ring substituent on the nitrogen. The …

A 2, 3-dichloro-5, 6-dicyano-1, 4-benzoquinone (DDQ)-catalysed electrochemical synthesis
of 2-amino-1, 3, 4-thiadiazoles from isothiocyanates and hydrazones is presented. This …

Un unsolvable issue of a significant number increase of drug multi resistant strains of
microorganisms including Mycobacterium tuberculosis force researchers for continuous …

A series of Schiff bases linked with heterocyclic moiety (6a–c, 7a–c, 11a–c, 12a–c, and 13a–
c) and ferrocenyl Schiff bases (15a–c) were designed, synthesized, and confirmed based on …