The importance of hydration and DNA conformation in interpreting infrared spectra of cells and tissues

BR Wood - Chemical Society Reviews, 2016 - pubs.rsc.org
Since Watson and Crick's historical papers on the structure and function of DNA based on
Rosalind Franklin's and Maurice Wilkin's X-ray diffraction patterns tremendous scientific …

Fundamental developments in infrared spectroscopic imaging for biomedical applications

M Pilling, P Gardner - Chemical Society reviews, 2016 - pubs.rsc.org
Infrared chemical imaging is a rapidly emerging field with new advances in instrumentation,
data acquisition and data analysis. These developments have had significant impact in …

Vibrational spectroscopic methods for cytology and cellular research

G Clemens, JR Hands, KM Dorling, MJ Baker - Analyst, 2014 - pubs.rsc.org
The use of vibrational spectroscopy, FTIR and Raman, for cytology and cellular research has
the potential to revolutionise the approach to cellular analysis. Vibrational spectroscopy is …

Transmission FT-IR chemical imaging on glass substrates: applications in infrared spectral histopathology

P Bassan, J Mellor, J Shapiro, KJ Williams… - Analytical …, 2014 - ACS Publications
Fourier transform-infrared (FT-IR) chemical imaging in transmission mode has traditionally
been performed on expensive mid-IR transparent windows such as barium/calcium fluoride …

Multivariate statistical methodologies applied in biomedical Raman spectroscopy: assessing the validity of partial least squares regression using simulated model …

ME Keating, H Nawaz, F Bonnier, HJ Byrne - Analyst, 2015 - pubs.rsc.org
Raman spectroscopy is fast becoming a valuable analytical tool in a number of biomedical
scenarios, most notably disease diagnostics. Importantly, the technique has also shown …

Infrared spectroscopy of live cells from a flowing solution using electrically-biased plasmonic metasurfaces

G Kelp, J Li, J Lu, N DiNapoli, R Delgado, C Liu, D Fan… - Lab on a Chip, 2020 - pubs.rsc.org
Spectral cytopathology (SCP) is a promising label-free technique for diagnosing diseases
and monitoring therapeutic outcomes using FTIR spectroscopy. In most cases, cells must be …

Application of metasurface-enhanced infra-red spectroscopy to distinguish between normal and cancerous cell types

G Kelp, N Arju, A Lee, E Esquivel, R Delgado, Y Yu… - Analyst, 2019 - pubs.rsc.org
Fourier transform infrared (FTIR) spectra of biological cells can reveal clinically important
information about cells' composition, including their normal or cancerous status. The recently …

Enhanced FTIR bench-top imaging of single biological cells

C Hughes, A Henderson, M Kansiz, KM Dorling… - Analyst, 2015 - pubs.rsc.org
A new optical system has recently been developed that enables infrared images to be
obtained with a pixel resolution of 1 micron on a bench-top instrument using a thermal …

Infrared micro-spectroscopy of human tissue: principles and future promises

M Diem, A Ergin, S Remiszewski, X Mu, A Akalin… - Faraday …, 2016 - pubs.rsc.org
This article summarizes the methods employed, and the progress achieved over the past
two decades in applying vibrational (Raman and IR) micro-spectroscopy to problems of …

Study of the biochemical effects induced by X-ray irradiations in combination with gadolinium nanoparticles in F98 glioma cells: first FTIR studies at the Emira …

I Yousef, O Seksek, S Gil, Y Prezado, J Sulé-Suso… - Analyst, 2016 - pubs.rsc.org
One strategy to improve the clinical outcome of radiotherapy is to use nanoparticles as
radiosensitizers. Along this line, numerous studies have shown the enhanced effectiveness …