Introduction Exploring the chemical diversity and molecular mechanisms of natural products
continues to be an important research area for identifying novel promising therapeutic …

Resistance to apoptosis stands as a roadblock to the successful pharmacological execution
of anticancer drug effect. A comprehensive insight into apoptotic signaling pathways and an …

Natural products have long been utilized in traditional medicine as remedies to improve
health and treat illnesses, and have had a key role in modern drug discovery. Recently …

Colorectal cancer (CRC) is a prevalent malignancy of the digestive tract with the second
highest mortality rate globally. Piper nigrum is a widely used traditional medicinal plant …

Chemotherapy resistance is still a serious problem in the treatment of most cancers. Many
cellular and molecular mechanisms contribute to both inherent and acquired drug …

Bacteriocins produced by lactic acid bacteria (LAB) are of interest due to their promising
applications in the food industry. In this study, Plantaricin FB-2 was separated to two …

The study of bioactive molecules of marine origin has created an important bridge between
biological knowledge and its applications in biotechnology and biomedicine. Current studies …

Angiogenesis is one of the defining characteristics of cancer. Vascular endothelial growth
factor (VEGF) is crucial for the development of angiogenesis. A growing interest in cancer …

Conventional chemotherapy, especially with natural anticancer drugs, usually suffers from
poor bioavailability and low tumor accumulation. To address these limitations, we developed …

Oenothein B (OeB) is a dimeric ellagitannin with potent antioxidative, antitumor,
immunomodulatory, and anti-inflammatory properties. Despite the promising activities of …