Natural products as a source of new anticancer chemotypes

F Melfi, S Carradori, N Mencarelli… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Exploring the chemical diversity and molecular mechanisms of natural products
continues to be an important research area for identifying novel promising therapeutic …

[HTML][HTML] Cooperatively inhibition effect of miR-143-5p and miR-145-5p in tumorigenesis of glioblastoma cells through modulating AKT signaling pathway

SJ Zaer, M Aghamaali, M Amini, MA Doustvandi… - BioImpacts …, 2024 - ncbi.nlm.nih.gov
Methods: U87 cells were cultured, and transfected with miR-143-5p and miR-145-5p.
Afterward, the changes in cell viability, and apoptosis induction were determined by MTT …

Does crocin create new hope for the treatment of oral problems? A focus on periodontitis

A Rekabi, A Ram, A Nazari, R Arefnezhad… - Molecular Biology …, 2024 - Springer
Abstract According to the World Health Organization (WHO) reports, oral health has an
indispensable role in the maintenance of human public health. However, oral problems …

MicroRNA-143 overexpression enhances the chemosensitivity of A172 glioblastoma cells to carmustine

SJ Zaer, M Aghamaali, S Najafi, SS Hosseini… - Naunyn-Schmiedeberg's …, 2024 - Springer
As an aggressive malignancy, glioblastoma multiforme (GBM) is the most common type of
brain tumor. The existing treatments have shown limited achievement in increasing the …

[HTML][HTML] Synthesis and Regulation of miRNA, Its Role in Oncogenesis, and Its Association with Colorectal Cancer Progression, Diagnosis, and Prognosis

M Rac - Diagnostics, 2024 - ncbi.nlm.nih.gov
The dysfunction of several types of regulators, including miRNAs, has recently attracted
scientific attention for their role in cancer-associated changes in gene expression. MiRNAs …

[PDF][PDF] Simultaneous effect of miR-21 suppression and miR-143 restoration on inhibition of proliferation and migration in SW-480 colorectal cancer cells

M Tohidast, M Amini, MA Doustvandi, SS Hosseini… - BioImpacts, 2024 - bi.tbzmed.ac.ir
Introduction: Colorectal cancer (CRC) is regarded as a serious global issue and is presently
ranked second in the classification of gastrointestinal (GI) malignancies, with fast incidence …