Targeting CD24/Siglec-10 signal pathway for cancer immunotherapy: recent advances and future directions

X Li, W Tian, Z Jiang, Y Song, X Leng, J Yu - Cancer Immunology …, 2024 - Springer
The small, heavily glycosylated protein CD24 is primarily expressed by many immune cells
and is highly expressed mostly in cancer cells. As one of the most crucial biomarkers of …

Targeting CD24 as a novel immunotherapy for solid cancers

Y Yang, G Zhu, L Yang, Y Yang - Cell Communication and Signaling, 2023 - Springer
Abstract Cluster of differentiation 24 (CD24), a mucin-like highly glycosylated molecule has
been extensively studied as a cancer stem cell marker in a variety of solid cancers. The …

Aucubin alleviates oxidative stress and inflammation via Nrf2-mediated signaling activity in experimental traumatic brain injury

H Wang, XM Zhou, LY Wu, GJ Liu, WD Xu… - Journal of …, 2020 - Springer
Abstract Background Aucubin (Au), an iridoid glycoside from natural plants, has
antioxidative and anti-inflammatory bioactivities; however, its effects on a traumatic brain …

Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury

G Sun, Z Miao, Y Ye, P Zhao, L Fan, Z Bao, Y Tu… - Brain Research …, 2020 - Elsevier
Cognitive decline is one of the most obvious symptoms of traumatic brain injury (TBI).
Previous studies have demonstrated that cognitive decline is related to substantially …

[HTML][HTML] CD24 as a potential therapeutic target in patients with B-cell leukemia and lymphoma: current insights

SL Christian - OncoTargets and therapy, 2022 - ncbi.nlm.nih.gov
CD24 is a highly glycosylated glycophosphatidylinositol (GPI)-anchored protein that is
expressed in many types of differentiating cells and some mature cells of the immune system …

Microglia-induced neuroinflammation in hippocampal neurogenesis following traumatic brain injury

SP Navabi, F Badreh, MK Shooshtari, S Hajipour… - Heliyon, 2024 - cell.com
Traumatic brain injury (TBI) is one of the most causes of death and disability among people,
leading to a wide range of neurological deficits. The important process of neurogenesis in …

Erianin promotes endogenous neurogenesis in traumatic brain injury rats

Q Li, X Gan, M Zhang, G Zhang, Y Li, L Gao - Scientific Reports, 2024 - nature.com
The objective of this study was to explore the positive influence and potential mechanism of
Erianin on the recovery of brain cells following a traumatic brain injury (TBI). TBI rat models …

Unravelling CD24‐Siglec‐10 pathway: Cancer immunotherapy from basic science to clinical studies

R Hazra, S Chattopadhyay, A Mallick, S Gayen… - …, 2024 - Wiley Online Library
Cancer immunotherapy has revolutionized the treatment landscape by harnessing the
power of the immune system to combat malignancies. Two of the most promising players in …

Knock-down of CD24 in astrocytes aggravates oxyhemoglobin-induced hippocampal neuron impairment

C Xiang-Xin, T Tao, G Sen, W Han, Z Xiao-Ming… - Neurochemical …, 2022 - Springer
Subarachnoid hemorrhage (SAH), as one of the most severe hemorrhagic strokes, is closely
related to neuronal damage. Neurogenesis is a promising therapy, however, reliable targets …

Melatonin mitigates manganese-induced neural damage via modulation of gut microbiota-metabolism in mice

W He, X Wang, X Yang, G Zhang, J Zhang… - Science of The Total …, 2024 - Elsevier
Manganese (Mn), a common environmental and occupational risk factor for Parkinson's
disease (PD), can cause central nervous system damage and gastrointestinal dysfunction …