New insights into atypical Alzheimer's disease in the era of biomarkers

J Graff-Radford, KXX Yong, LG Apostolova… - The Lancet …, 2021 - thelancet.com
Most patients with Alzheimer's disease present with amnestic problems; however, a
substantial proportion, over-represented in young-onset cases, have atypical phenotypes …

The complexity of Alzheimer's disease: an evolving puzzle

C Ferrari, S Sorbi - Physiological reviews, 2021 - journals.physiology.org
The history of Alzheimer's disease (AD) started in 1907, but we needed to wait until the end
of the century to identify the components of pathological hallmarks and genetic subtypes and …

Clinical neurology and epidemiology of the major neurodegenerative diseases

MG Erkkinen, MO Kim… - Cold Spring Harbor …, 2018 - cshperspectives.cshlp.org
Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Frontotemporal dementia

NT Olney, S Spina, BL Miller - Neurologic clinics, 2017 - neurologic.theclinics.com
Frontotemporal dementia (FTD) has undergone numerous changes in nomenclature and
categorization schemes since it was first described by Pick in 1892. Presently, FTD …

Criteria for the diagnosis of corticobasal degeneration

MJ Armstrong, I Litvan, AE Lang, TH Bak, KP Bhatia… - Neurology, 2013 - AAN Enterprises
Current criteria for the clinical diagnosis of pathologically confirmed corticobasal
degeneration (CBD) no longer reflect the expanding understanding of this disease and its …

Parkinson's disease and parkinsonism: neuropathology

DW Dickson - Cold Spring Harbor perspectives …, 2012 - perspectivesinmedicine.cshlp.org
Parkinsonism, the clinical term for a disorder with prominent bradykinesia and variable
associated extrapyramidal signs and symptoms, is accompanied by degeneration of the …

Tau PET imaging: present and future directions

L Saint-Aubert, L Lemoine, K Chiotis, A Leuzy… - Molecular …, 2017 - Springer
Abnormal aggregation of tau in the brain is a major contributing factor in various
neurodegenerative diseases. The role of tau phosphorylation in the pathophysiology of …

Measuring the thickness of the human cerebral cortex from magnetic resonance images

B Fischl, AM Dale - Proceedings of the National Academy of …, 2000 - National Acad Sciences
Accurate and automated methods for measuring the thickness of human cerebral cortex
could provide powerful tools for diagnosing and studying a variety of neurodegenerative and …

Reliability of MRI-derived measurements of human cerebral cortical thickness: the effects of field strength, scanner upgrade and manufacturer

X Han, J Jovicich, D Salat, A van der Kouwe, B Quinn… - Neuroimage, 2006 - Elsevier
In vivo MRI-derived measurements of human cerebral cortex thickness are providing novel
insights into normal and abnormal neuroanatomy, but little is known about their reliability …

The accuracy of diagnosis of parkinsonian syndromes in a specialist movement disorder service

AJ Hughes, SE Daniel, Y Ben‐Shlomo, AJ Lees - Brain, 2002 - academic.oup.com
We have reviewed the clinical and pathological diagnoses of 143 cases of parkinsonism
seen by neurologists associated with the movement disorders service at The National …