The aquatic environment holds a vast source of organisms that provide numerous
opportunities to bioprospect new molecules. Notably, fish are producers of an epidermal …

Background Despite the growing productivity of aquaculture, economic losses due to
infectious diseases, environmental pollution, and human safety concerns related to antibiotic …

Identifying bioactive molecules from marine organisms is still vastly understudied. Fish
remain an untapped source of bioactive molecules, even when considering species whose …

Antimicrobial peptides (AMPs) are considered to be amongst the most powerful tools for the
fight against pathogens in fish, since they form part of the innate immune response, which is …

The function of histones is well-known in the folding and packaging of DNA, gene regulation,
tumor formation, and apoptosis and they also have bactericidal properties. In the present …

NK-lysins are one of the most abundant antimicrobial peptides produced by cytotoxic T
lymphocytes (CTLs) and natural killer cells (NKs), and identified as a new class of …

Sexual dimorphism in immunity has been extensively documented across vertebrates, with
marked contrasts observed in immune responses between males and females. These …

NK-lysin is an important part of the innate immune defence system and plays an important
role in resisting the invasion of pathogenic microorganisms. In this study, NK-lysin from …

NK-lysins (NKLs) are a family of multifunctional antimicrobial peptides that have activity
against various microorganisms. However, the immunomodulatory activity of NKL in fish …

Abstract Fish NK-lysin (NKL), an orthologous to human granulysin, exerts a dual role as an
antimicrobial peptide (AMP) and as a direct executor of T cytotoxic and natural killer cells …