Virtual clinical trials in medical imaging: a review

E Abadi, WP Segars, BMW Tsui… - Journal of Medical …, 2020 - spiedigitallibrary.org
The accelerating complexity and variety of medical imaging devices and methods have
outpaced the ability to evaluate and optimize their design and clinical use. This is a …

Application of the 4-D XCAT phantoms in biomedical imaging and beyond

WP Segars, BMW Tsui, J Cai, FF Yin… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
The four-dimensional (4-D) eXtended CArdiac-Torso (XCAT) series of phantoms was
developed to provide accurate computerized models of the human anatomy and physiology …

MRXCAT: Realistic numerical phantoms for cardiovascular magnetic resonance

L Wissmann, C Santelli, WP Segars… - Journal of Cardiovascular …, 2014 - Springer
Background Computer simulations are important for validating novel image acquisition and
reconstruction strategies. In cardiovascular magnetic resonance (CMR), numerical …

A virtual imaging platform for multi-modality medical image simulation

T Glatard, C Lartizien, B Gibaud… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
This paper presents the Virtual Imaging Platform (VIP), a platform accessible at http://vip.
creatis. insa-lyon. fr to facilitate the sharing of object models and medical image simulators …

A high-resolution atlas and statistical model of the human heart from multislice CT

C Hoogendoorn, N Duchateau… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
Atlases and statistical models play important roles in the personalization and simulation of
cardiac physiology. For the study of the heart, however, the construction of comprehensive …

Model-based generation of large databases of cardiac images: synthesis of pathological cine MR sequences from real healthy cases

N Duchateau, M Sermesant… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
Collecting large databases of annotated medical images is crucial for the validation and
testing of feature extraction, statistical analysis, and machine learning algorithms. Recent …

A framework for the generation of realistic synthetic cardiac ultrasound and magnetic resonance imaging sequences from the same virtual patients

Y Zhou, S Giffard-Roisin, M De Craene… - IEEE transactions on …, 2017 - ieeexplore.ieee.org
The use of synthetic sequences is one of the most promising tools for advanced in silico
evaluation of the quantification of cardiac deformation and strain through 3-D ultrasound …

4D semantic cardiac magnetic resonance image synthesis on XCAT anatomical model

S Abbasi-Sureshjani, S Amirrajab… - … Imaging with Deep …, 2020 - proceedings.mlr.press
We propose a hybrid controllable image generation method to synthesize anatomically
meaningful 3D+ t labeled Cardiac Magnetic Resonance (CMR) images. Our hybrid method …

Generation of synthetic but visually realistic time series of cardiac images combining a biophysical model and clinical images

A Prakosa, M Sermesant, H Delingette… - IEEE transactions on …, 2012 - ieeexplore.ieee.org
We propose a new approach for the generation of synthetic but visually realistic time series
of cardiac images based on an electromechanical model of the heart and real clinical 4-D …

MRXCAT2. 0: Synthesis of realistic numerical phantoms by combining left-ventricular shape learning, biophysical simulations and tissue texture generation

S Buoso, T Joyce, N Schulthess, S Kozerke - Journal of Cardiovascular …, 2023 - Springer
Background Standardised performance assessment of image acquisition, reconstruction
and processing methods is limited by the absence of images paired with ground truth …