ESR1gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients

J Martínez-Galán, B Torres-Torres, MI Núñez… - BMC cancer, 2014 - Springer
Background Tumor expression of estrogen receptor (ER) is an important marker of
prognosis, and is predictive of response to endocrine therapy in breast cancer. Several …

The most common genes involved in epigenetics modifications among Iranian patients with breast cancer: A systematic review

N Iranshahi, P Zafari, KH Yari… - Cellular and Molecular …, 2016 - cellmolbiol.org
Breast cancer, with a lifelong risk of one in nine, is the most common cancer among women.
In Iran, breast cancer is one of the growing and important women's health problems. Several …

[HTML][HTML] Glucocorticoid induced loss of oestrogen receptor alpha gene methylation and restoration of sensitivity to fulvestrant in triple negative breast cancer

H Intabli, JM Gee, S Oesterreich, MS Yeoman… - Gene, 2023 - Elsevier
The response to psychological stress can differ depending on the type and duration of the
stressor. Acute stress can facilitate a “fight or flight response” and aid survival, whereas …

In silico docking studies of selected flavonoids-natural healing agents against breast cancer

J Suganya, M Radha, DL Naorem… - Asian Pacific Journal of …, 2014 - koreascience.kr
Background: Breast cancer is the serious health concern in India causing the highest
mortality rate in females, which occurs due to uncontrolled cell division and can be …

PTPRO promoter methylation is predictive of poorer outcome for HER2-positive breast cancer: indication for personalized therapy

YT Huang, FF Li, C Ke, Z Li, ZT Li, XF Zou… - Journal of translational …, 2013 - Springer
Abstract Background Protein Tyrosine Phosphatase Receptor-type O (PTPRO) has recently
been in the spotlight as a tumor suppressor, whose encoding gene is frequently methylated …

Targeting the epigenome as a novel therapeutic approach for breast cancer

S Oh, JY Ko, C Oh, KH Yoo - Translational Research in Breast Cancer …, 2017 - Springer
Breast cancer is one of complex diseases that are influenced by environment. Various
genetic and epigenetic alterations are provoking causes of breast carcinogenesis. Dynamic …

BRCA1 promoter hypermethylation signature for early detection of breast cancer in the Vietnamese population

PK Truong, TD Lao, TPT Doan… - Asian Pacific Journal of …, 2014 - koreascience.kr
Breast cancer, a leading cause of death among women in most countries worldwide, is
rapidly increasing in incidence in Vietnam. One of biomarkers is the disruption of the genetic …

Estrogen receptor alpha (ERα) promoter methylation status in tumor and serum DNA in Egyptian breast cancer patients

HA Hagrass, HF Pasha, AM Ali - Gene, 2014 - Elsevier
Background Status of DNA methylation is one of the most common molecular alterations in
human neoplasia. Because it is possible to detect these epigenetic alterations in the …

Loss of expression of cyclin d2 by aberrant DNA methylation: a potential biomarker in vietnamese breast cancer patients

PK Truong, TD Lao, TPT Doan… - Asian Pacific Journal of …, 2015 - koreascience.kr
DNA methylation of tumor suppressor gene promoters is the most frequent phenomenon
leading to inactivation of function, consequently driving malignant cell transformation. Cyclin …

Association of poor prognosis subtypes of breast cancer with estrogen receptor alpha methylation in Iranian women

P Izadi, M Noruzinia, F Fereidooni… - Asian Pacific Journal of …, 2012 - koreascience.kr
Breast cancer is a prevalent heterogeneous malignant disease. Gene expression profiling
by DNA microarray can classify breast tumors into five different molecular subtypes: luminal …