Lapachol is a naturally occurring 1, 4-naphthoquinone originally isolated by the Italian
phytochemist E. Paterno from Tabebuia avellanedae (Bignoniaceae) in 1882 and …

Naphthoquinones are naturally occurring biologically active entities. Practical de novo
syntheses of three naphthoquinones ie lawsone (1), lapachol (2), and β-lapachone (3b) …

A series of 36 new phenylsulfanylmethyl [1, 4] naphthoquinones (7–42) were synthesized by
a three-component reaction that involves lawsone, the appropriate aldehyde and thiols with …

This review involves the chemistry and biochemistry of lapachol, β-lapachone and lawsone,
examples of bioactive natural products that still being under biological evaluation and …

2-Hydroxy-1,4-naphthoquinone: A Versatile Synthon in Organic Synthesis Page 1 Send Orders
for Reprints to reprints@benthamscience.ae 1314 Current Organic Chemistry, 2016, 20 …

An environmentally benign system for the direct alkylation of lawsones and 4-
hydroxycoumarins with alcohols in 1, 1, 1, 3, 3, 3-hexafluoroisopropanol (HFIP) is reported …

Background The hydroxynaphthoquinones have been extensively investigated over the past
50 years for their anti-malarial activity. One member of this class, atovaquone, is combined …

The oral squamous cell carcinoma (OSCC) stands out as a public health problem due to its
high incidence and low survival rate, despite advances in diagnosis and treatment …

Leukemia is the most common blood cancer, and its development starts at diverse points,
leading to distinct subtypes that respond differently to therapy. This heterogeneity is rarely …

The bioactive naphtoquinone lapachol was studied in vitro by a biomimetic model with
Jacobsen catalyst (manganese (III) salen) and iodosylbenzene as oxidizing agent. Eleven …