Cellular senescence is a cell fate triggered in response to stress and is characterized by
stable cell-cycle arrest and a hypersecretory state. It has diverse biological roles, ranging …

Cellular senescence is a critical stress response program implicated in embryonic
development, wound healing, aging, and immunity, and it backs up apoptosis as an ultimate …

Non-small cell lung cancer (NSCLC) constitutes one of the deadliest and most common
malignancies. The LKB1/STK11 tumour suppressor is mutated in∼ 30% of NSCLCs …

The emerging field of senolytics is centered on eliminating senescent cells to block their
contribution to the progression of age-related diseases, including cancer, and to facilitate …

Cellular senescence has been increasingly recognized as a hallmark of cancer, reflecting its
association with aging and inflammation, its role as a response to deregulated proliferation …

Cellular senescence is a state of permanent growth arrest. It can be triggered by telomere
shortening (replicative senescence) or prematurely induced by stresses such as DNA …

Senescence is an inherent cellular mechanism triggered as a response to stressful insults. It
associates with several aspects of cancer progression and therapy. Senescent cells …

Cell immortalization has an important role in scientific research, as well as increasing
significance in the context of cell therapy and biotechnology. Over the years, many …

Senescence is a crucial hallmark of ageing and a significant contributor to the pathology of
age-related disorders. As committee members of the young International Cell Senescence …

The intricate relationship between cancer, circadian rhythms, and aging is increasingly
recognized as a critical factor in understanding the mechanisms underlying tumorigenesis …