Site-selective modification strategies in antibody–drug conjugates

SJ Walsh, JD Bargh, FM Dannheim… - Chemical Society …, 2021 - pubs.rsc.org
Antibody–drug conjugates (ADCs) harness the highly specific targeting capabilities of an
antibody to deliver a cytotoxic payload to specific cell types. They have garnered …

What's new in chitinase research?

J Flach, PE Pilet, P Jolles - Experientia, 1992 - Springer
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Catalytic mechanism of enzymic glycosyl transfer

ML Sinnott - Chemical Reviews, 1990 - ACS Publications
At least in terms of simple tonnage, glycosyl transfer must be accounted one of the most
important biochemical reactions, since around two-thirds of the carbon in the biosphere …

Silk fibroin of Bombyx mori is secreted, assembling a high molecular mass elementary unit consisting of H-chain, L-chain, and P25, with a 6: 6: 1 molar ratio

S Inoue, K Tanaka, F Arisaka, S Kimura… - Journal of Biological …, 2000 - ASBMB
Silk fibroin produced by the silkwormBombyx mori consists of a heavy chain, a light chain,
and a glycoprotein, P25. The heavy and light chains are linked by a disulfide bond, and P25 …

Chitinase is required for cell separation during growth of Saccharomyces cerevisiae.

MJ Kuranda, PW Robbins - Journal of Biological Chemistry, 1991 - ASBMB
The Saccharomyces cerevisiae chitinase described by Correa et al.(Correa, JU, Elango, N.,
Polacheck, I., and Cabib, E.(1982) J. Biol. Chem. 257, 1392-1397) has been cloned and …

Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus

MJ Bibb, GR Janssen, JM Ward - Gene, 1985 - Elsevier
A DNA fragment containing the coding and regulatory sequences of the erythromycin (Er)
resistance (ermE) gene of the Er produces Streptomyces erythraeus was cloned in …

Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses

J Dubuisson, HH Hsu, RC Cheung… - Journal of …, 1994 - Am Soc Microbiol
Hepatitis C virus (HCV) encodes two putative virion glycoproteins (E1 and E2) which are
released from the polyprotein by signal peptidase cleavage. In this report, we have …

Insect chitin: physical state, synthesis, degradation and metabolic regulation

KJ Kramer, D Koga - Insect biochemistry, 1986 - Elsevier
" The shock arose not from the creatures abilities (intelligence, calculation, cunning and
aggressiveness) but from the fact that they possessed internal skeletons, leathery skins and …

Identification of glutamic acid 204 and aspartic acid 200 in chitinase A1 of Bacillus circulans WL-12 as essential residues for chitinase activity.

T Watanabe, K Kobori, K Miyashita, T Fujii… - Journal of Biological …, 1993 - ASBMB
Prokaryotic chitinases, class III plant chitinases, yeast chitinases, and endo-beta-N-
acetylglucosaminidases share weak amino acid sequence similarities at the certain region …

Sequence of a cDNA and expression of the gene encoding epidermal and gut chitinases of Manduca sexta

KJ Kramer, L Corpuz, HK Choi… - Insect Biochemistry and …, 1993 - Elsevier
Insects use chitinolytic enzymes to digest chitin in the exoskeleton during the molting
process. We have isolated and sequenced a chitinase-encoding cDNA from the tobacco …