Advances in closed-loop deep brain stimulation devices

M Parastarfeizabadi, AZ Kouzani - Journal of neuroengineering and …, 2017 - Springer
Background Millions of patients around the world are affected by neurological and
psychiatric disorders. Deep brain stimulation (DBS) is a device-based therapy that could …

Medical and surgical management of advanced Parkinson's disease

A Antonini, E Moro, C Godeiro… - Movement …, 2018 - Wiley Online Library
Advanced Parkinson's disease is characterized by the presence of motor fluctuations,
various degree of dyskinesia, and disability with functional impact on activities of daily living …

Adaptive deep brain stimulation in advanced Parkinson disease

S Little, A Pogosyan, S Neal, B Zavala… - Annals of …, 2013 - Wiley Online Library
Objective Brain–computer interfaces (BCIs) could potentially be used to interact with
pathological brain signals to intervene and ameliorate their effects in disease states. Here …

Subthalamic synchronized oscillatory activity correlates with motor impairment in patients with Parkinson's disease

WJ Neumann, K Degen, GH Schneider… - Movement …, 2016 - Wiley Online Library
Objective Beta band oscillations in the subthalamic nucleus (STN) have been proposed as a
pathophysiological signature in patients with Parkinson's disease (PD). The aim of this study …

Towards adaptive deep brain stimulation: clinical and technical notes on a novel commercial device for chronic brain sensing

Y Thenaisie, C Palmisano, A Canessa… - Journal of Neural …, 2021 - iopscience.iop.org
Objective. Technical advances in deep brain stimulation (DBS) are crucial to improve
therapeutic efficacy and battery life. We report the potentialities and pitfalls of one of the first …

Beta oscillations in freely moving Parkinson's subjects are attenuated during deep brain stimulation

EJ Quinn, Z Blumenfeld, A Velisar, MM Koop… - Movement …, 2015 - Wiley Online Library
Background Investigations into the effect of deep brain stimulation (DBS) on subthalamic
(STN) beta (13‐30 Hz) oscillations have been performed in the perioperative period with the …

Alterations in neuronal activity in basal ganglia-thalamocortical circuits in the parkinsonian state

A Galvan, A Devergnas, T Wichmann - Frontiers in neuroanatomy, 2015 - frontiersin.org
In patients with Parkinson's disease and in animal models of this disorder, neurons in the
basal ganglia and related regions in thalamus and cortex show changes that can be …

[HTML][HTML] Adaptive deep brain stimulation in a freely moving parkinsonian patient

M Rosa, M Arlotti, G Ardolino, F Cogiamanian… - Movement …, 2015 - ncbi.nlm.nih.gov
The future of deep brain stimulation (DBS) for Parkinson's disease (PD) lies in new closed-
loop systems that continuously supply the implanted stimulator with new settings obtained …

A convolutional-recurrent neural network approach to resting-state EEG classification in Parkinson's disease

S Lee, R Hussein, R Ward, ZJ Wang… - Journal of neuroscience …, 2021 - Elsevier
Background Parkinson's disease (PD) is expected to become more common, particularly
with an aging population. Diagnosis and monitoring of the disease typically rely on the …

Principles of gait encoding in the subthalamic nucleus of people with Parkinson's disease

Y Thenaisie, K Lee, C Moerman, S Scafa… - Science translational …, 2022 - science.org
Disruption of subthalamic nucleus dynamics in Parkinson's disease leads to impairments
during walking. Here, we aimed to uncover the principles through which the subthalamic …