Survey of the year 2004: literature on applications of isothermal titration calorimetry

A Ababou, JE Ladbury - Journal of Molecular Recognition: An …, 2006 - Wiley Online Library
The market for commercially available isothermal titration calorimeters continues to grow as
new applications and methodologies are developed. Concomitantly the number of users …

Multiple roles for frequenin/NCS-1 in synaptic function and development

JS Dason, J Romero-Pozuelo, HL Atwood… - Molecular …, 2012 - Springer
The calcium-binding protein frequenin (Frq), discovered in the fruit fly Drosophila, and its
mammalian homologue neuronal calcium sensor 1 (NCS-1) have been reported to affect …

The 3A protein from multiple picornaviruses utilizes the golgi adaptor protein ACBD3 to recruit PI4KIIIβ

AL Greninger, GM Knudsen, M Betegon… - Journal of …, 2012 - Am Soc Microbiol
The activity of phosphatidylinositol 4-kinase class III beta (PI4KIIIβ) has been shown to be
required for the replication of multiple picornaviruses; however, it is unclear whether a …

Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium

C Schlecker, W Boehmerle, A Jeromin… - The Journal of …, 2006 - Am Soc Clin Investig
Regulation and dysregulation of intracellular calcium (Ca2+) signaling via the inositol 1, 4, 5-
trisphosphate receptor (InsP3R) has been linked to many cellular processes and …

Regulatory and structural EF-hand motifs of neuronal calcium sensor-1: Mg2+ modulates Ca2+ binding, Ca2+-induced conformational changes, and equilibrium …

P Aravind, K Chandra, PP Reddy, A Jeromin… - Journal of molecular …, 2008 - Elsevier
Neuronal calcium sensor-1 (NCS-1) is a major modulator of Ca2+ signaling with a known
role in neurotransmitter release. NCS-1 has one cryptic (EF1) and three functional (EF2 …

Novel role of neuronal Ca2+ sensor-1 as a survival factor up-regulated in injured neurons

TY Nakamura, A Jeromin, G Smith… - The Journal of cell …, 2006 - rupress.org
A molecular basis of survival from neuronal injury is essential for the development of
therapeutic strategy to remedy neurodegenerative disorders. In this study, we demonstrate …

A myristoyl/phosphoserine switch controls cAMP-dependent protein kinase association to membranes

EC Gaffarogullari, LR Masterson, EE Metcalfe… - Journal of molecular …, 2011 - Elsevier
The cAMP-dependent protein kinase [protein kinase A (PKA)] mediates a myriad of cellular
signaling events, and its activity is tightly regulated in both space and time. Among these …

Functional status of neuronal calcium sensor-1 is modulated by zinc binding

PO Tsvetkov, AY Roman, VE Baksheeva… - Frontiers in Molecular …, 2018 - frontiersin.org
Neuronal calcium sensor-1 (NCS-1) protein is abundantly expressed in the central nervous
system and retinal neurons, where it regulates many vital processes such as synaptic …

Nanomolar affinity of EF-hands in neuronal calcium sensor 1 for bivalent cations Pb2+, Mn2+, and Hg2+

MS Alam, S Azam, K Pham, D Leyva, KJD Fouque… - Metallomics, 2022 - academic.oup.com
Abstract Abiogenic metals Pb and Hg are highly toxic since chronic and/or acute exposure
often leads to severe neuropathologies. Mn2+ is an essential metal ion but in excess can …

Calcium binds to leptospiral immunoglobulin-like protein, LigB, and modulates fibronectin binding

YP Lin, R Raman, Y Sharma, YF Chang - Journal of Biological Chemistry, 2008 - ASBMB
Pathogenic Leptospira spp. express immunoglobulin-like proteins, LigA and LigB, which
serve as adhesins to bind to extracellular matrices and mediate their attachment on host …