Nanotechnology advances towards development of targeted-treatment for obesity

NRS Sibuyi, KL Moabelo, M Meyer, MO Onani… - Journal of …, 2019 - Springer
Obesity through its association with type 2 diabetes (T2D), cancer and cardiovascular
diseases (CVDs), poses a serious health threat, as these diseases contribute to high …

Mesoporous systems for poorly soluble drugs–recent trends

J Riikonen, W Xu, VP Lehto - International journal of pharmaceutics, 2018 - Elsevier
When poor aqueous solubility of active pharmaceutical ingredients is encountered during a
drug formulation process, the toolbox typically utilized contains pharmaceutical salts, co …

3D-printed mesoporous carrier system for delivery of poorly soluble drugs

CS Katsiotis, M Åhlén, M Strømme, K Welch - Pharmaceutics, 2021 - mdpi.com
Fused deposition modelling (FDM) is the most extensively employed 3D-printing technique
used in pharmaceutical applications, and offers fast and facile formulation development of …

Evaluation of suitable polymeric matrix/carriers during loading of poorly water soluble drugs onto mesoporous silica: Physical stability and in vitro supersaturation

A Kapourani, K Katopodis, V Valkanioti… - Polymers, 2024 - mdpi.com
The application of mesoporous carriers in formulations of amorphous solid dispersions
(ASDs) has been suggested to enhance the stability of amorphous drugs. However …

[HTML][HTML] An in vitro dissolution–digestion–permeation assay for the study of advanced drug delivery systems

C Alvebratt, J Keemink, K Edueng, O Cheung… - European Journal of …, 2020 - Elsevier
Advanced drug delivery systems (ADDS) are widely explored to overcome poor aqueous
solubility of orally administered drugs. However, the prediction of their in vivo performance is …

[HTML][HTML] Processability of mesoporous materials in fused deposition modeling for drug delivery of a model thermolabile drug

CS Katsiotis, M Strømme, K Welch - International Journal of Pharmaceutics …, 2023 - Elsevier
The incorporation of drug-loaded mesoporous materials in dosage forms prepared with
fused deposition modeling (FDM) has shown the potential to solve challenges relating to …

Tolfenamic acid

S Ahmed, MA Sheraz, I Ahmad - Profiles of Drug Substances, Excipients …, 2018 - Elsevier
Tolfenamic acid (TA) is a nonsteroidal antiinflammatory drug and belongs to the group of
fenamates. It is used as a potent pain reliever in the treatment of acute migraine attacks, and …

[HTML][HTML] Development of a simple paste for 3D printing of drug formulations containing a mesoporous material loaded with a poorly water-soluble drug

CS Katsiotis, E Tikhomirov, C Leliopoulos… - European Journal of …, 2024 - Elsevier
Poorly soluble drugs represent a substantial portion of emerging drug candidates, posing
significant challenges for pharmaceutical formulators. One promising method to enhance the …

Crosslinking ionic oligomers sol-gel synthesis of high-surface-area mesoporous magnesium carbonate and its general applicability

G Chen, Z Kang, C Liu, J Yu, Q Wang, J Liu… - … and Mesoporous Materials, 2024 - Elsevier
Mesoporous magnesium carbonate has been widely used in controlled release of drugs,
adsorption or catalysis. In traditional methods, expensive alkoxide or MgO are usually …

Synthesis and characterization of amorphous magnesium carbonate nanoparticles

J Yang, Y Han, J Luo, K Leifer, M Strømme… - Materials Chemistry and …, 2019 - Elsevier
We report the template-free, low-temperature, environment-friendly synthesis of amorphous
magnesium carbonate nanoparticles (AMN). Scanning electron microscopy and …