Reactive oxygen species (ROS)-based nanomedicine

B Yang, Y Chen, J Shi - Chemical reviews, 2019 - ACS Publications
Reactive oxygen species (ROS) play an essential role in regulating various physiological
functions of living organisms. The intrinsic biochemical properties of ROS, which underlie …

Recent advances on endogenous/exogenous stimuli-triggered nanoplatforms for enhanced chemodynamic therapy

Q Sun, Z Wang, B Liu, F He, S Gai, P Yang… - Coordination Chemistry …, 2022 - Elsevier
In view of certain unique internalization features of the tumor microenvironment
(TME)(mainly including hypoxia, acidity and higher concentrations of H 2 O 2 and GSH) …

Renal clearable ultrasmall single-crystal Fe nanoparticles for highly selective and effective ferroptosis therapy and immunotherapy

H Liang, X Wu, G Zhao, K Feng, K Ni… - Journal of the American …, 2021 - ACS Publications
Iron-based nanoparticles have attracted much attention because of their ability to induce
ferroptosis via a catalyzing Fenton reaction and to further potentiate immunotherapy …

Self-Assembled Copper–Amino Acid Nanoparticles for in Situ Glutathione “AND” H2O2 Sequentially Triggered Chemodynamic Therapy

B Ma, S Wang, F Liu, S Zhang, J Duan… - Journal of the …, 2018 - ACS Publications
Nanoformulations that can respond to the specific tumor microenvironment (TME), such as a
weakly acidic pH, low oxygen, and high glutathione (GSH), show promise for killing cancer …

Simultaneous Fenton‐like Ion Delivery and Glutathione Depletion by MnO2‐Based Nanoagent to Enhance Chemodynamic Therapy

LS Lin, J Song, L Song, K Ke, Y Liu, Z Zhou… - Angewandte …, 2018 - Wiley Online Library
Chemodynamic therapy (CDT) utilizes iron‐initiated Fenton chemistry to destroy tumor cells
by converting endogenous H2O2 into the highly toxic hydroxyl radical (. OH). There is a …

Cancer treatment through nanoparticle-facilitated fenton reaction

H Ranji-Burachaloo, PA Gurr, DE Dunstan, GG Qiao - ACS nano, 2018 - ACS Publications
Currently, cancer is the second largest cause of death worldwide and has reached critical
levels. In spite of all the efforts, common treatments including chemotherapy, photodynamic …

Enzyme mimicry for combating bacteria and biofilms

Z Chen, Z Wang, J Ren, X Qu - Accounts of Chemical Research, 2018 - ACS Publications
Conspectus Bacterial infection continues to be a growing global health problem with the
most widely accepted treatment paradigms restricted to antibiotics. However, antibiotics …

Observing crystal nucleation in four dimensions using atomic electron tomography

J Zhou, Y Yang, Y Yang, DS Kim, A Yuan, X Tian… - Nature, 2019 - nature.com
Nucleation plays a critical role in many physical and biological phenomena that range from
crystallization, melting and evaporation to the formation of clouds and the initiation of …

Nanocatalysts-augmented Fenton chemical reaction for nanocatalytic tumor therapy

X Qian, J Zhang, Z Gu, Y Chen - Biomaterials, 2019 - Elsevier
It is the challenging goal in cancer biomedicine to search novel cancer-therapeutic modality
with concurrent high therapeutic efficiency on combating cancer and low side effects to …

Platinum nanoparticles in nanobiomedicine

D Pedone, M Moglianetti, E De Luca, G Bardi… - Chemical Society …, 2017 - pubs.rsc.org
Oxidative stress-dependent inflammatory diseases represent a major concern for the
population's health worldwide. Biocompatible nanomaterials with enzymatic properties …