ATAC-king the complexity of SAGA during evolution
G Spedale, HTM Timmers… - Genes & …, 2012 - genesdev.cshlp.org
The yeast SAGA (Spt–Ada–Gcn5–acetyltransferase) coactivator complex exerts functions in
gene expression, including activator interaction, histone acetylation, histone …
gene expression, including activator interaction, histone acetylation, histone …
[HTML][HTML] The nucleosome remodeling factor
SG Alkhatib, JW Landry - FEBS letters, 2011 - Elsevier
An essential component of the chromatin remodeling machinery is NURF (Nucleosome
Remodeling Factor), the founding member of the ISWI family of chromatin remodeling …
Remodeling Factor), the founding member of the ISWI family of chromatin remodeling …
Interleukin-2 improves amyloid pathology, synaptic failure and memory in Alzheimer's disease mice
S Alves, G Churlaud, M Audrain… - Brain, 2017 - academic.oup.com
Abstract Interleukin-2 (IL-2)-deficient mice have cytoarchitectural hippocampal modifications
and impaired learning and memory ability reminiscent of Alzheimer's disease. IL-2 …
and impaired learning and memory ability reminiscent of Alzheimer's disease. IL-2 …
Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein
Eukaryotic GCN5 acetyltransferases influence diverse biological processes by acetylating
histones and non-histone proteins and regulating chromatin and gene-specific transcription …
histones and non-histone proteins and regulating chromatin and gene-specific transcription …
BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis
L Richart, E Carrillo-de Santa Pau… - Nature …, 2016 - nature.com
Abstract c-MYC oncogene is deregulated in most human tumours. Histone marks associated
with transcriptionally active genes define high-affinity c-MYC targets. The mechanisms …
with transcriptionally active genes define high-affinity c-MYC targets. The mechanisms …
The metazoan ATAC and SAGA coactivator HAT complexes regulate different sets of inducible target genes
Z Nagy, A Riss, S Fujiyama, A Krebs, M Orpinell… - Cellular and Molecular …, 2010 - Springer
Histone acetyl transferases (HATs) play a crucial role in eukaryotes by regulating chromatin
architecture and locus-specific transcription. The GCN5 HAT was identified as a subunit of …
architecture and locus-specific transcription. The GCN5 HAT was identified as a subunit of …
NURF301 contributes to gypsy chromatin insulator-mediated nuclear organization
S Chen, LF Rosin, G Pegoraro… - Nucleic Acids …, 2022 - academic.oup.com
Chromatin insulators are DNA-protein complexes that can prevent the spread of repressive
chromatin and block communication between enhancers and promoters to regulate gene …
chromatin and block communication between enhancers and promoters to regulate gene …
[HTML][HTML] Chromatin remodelers fine-tune H3K36me-directed deacetylation of neighbor nucleosomes by Rpd3S
Chromatin remodelers have been implicated in the regulation of histone-modifying
complexes. However, the underlying mechanism remains poorly understood. The Rpd3S …
complexes. However, the underlying mechanism remains poorly understood. The Rpd3S …
Identical Functional Organization of Nonpolytene and Polytene Chromosomes in Drosophila melanogaster
TY Vatolina, LV Boldyreva, OV Demakova… - PloS one, 2011 - journals.plos.org
Salivary gland polytene chromosomes demonstrate banding pattern, genetic meaning of
which is an enigma for decades. Till now it is not known how to mark the band/interband …
which is an enigma for decades. Till now it is not known how to mark the band/interband …
The activation potential of MOF is constrained for dosage compensation
Summary The H4K16 acetyltransferase MOF plays a crucial role in dosage compensation in
Drosophila but has additional, global functions. We compared the molecular context and …
Drosophila but has additional, global functions. We compared the molecular context and …