Meta-analysis of Pregnancy Events in Biomedical HIV Prevention Trials in Sub-Saharan Africa: Implications for Gender Transformative Trials

L Lorenzetti, N Dinh, C Whitcomb, A Martinez… - AIDS and Behavior, 2024 - Springer
Historically, pregnant and lactating populations (PLP) have been excluded or disenrolled
from biomedical HIV prevention trials, despite being more likely to acquire HIV during …

Meta-analysis of effect sizes reported at multiple time points using general linear mixed model

A Musekiwa, SOM Manda, HG Mwambi, DG Chen - PloS one, 2016 - journals.plos.org
Meta-analysis of longitudinal studies combines effect sizes measured at pre-determined
time points. The most common approach involves performing separate univariate meta …

Contraceptive use, prevalence and incidence of pregnancy and associated factors among women participating in a vaccine preparedness cohort study in Masaka …

S Kusemererwa, S Kansiime, S Nakamanya… - Reproductive health, 2024 - Springer
Background HIV prevention trials usually require that women of childbearing potential use
an effective method of contraception. This is because the effect of most investigational …

Preventing HIV Infection in Pregnant Women in Western Uganda Through a Comprehensive Antenatal Care-Based Intervention: An Implementation Study

LS Jahn, A Kengonzi, SN Kabwama… - Archives of Sexual …, 2024 - Springer
We implemented and assessed a comprehensive, antenatal care (ANC)-embedded strategy
to prevent HIV seroconversions during pregnancy in Uganda. HIV-negative first-time ANC …

Implementation of a prospective pregnancy registry for antiretroviral based HIV prevention trials

FG Mhlanga, L Noguchi, JE Balkus, S Kabwigu… - HIV clinical …, 2018 - Taylor & Francis
Background: Safety data on pregnancy and fetal outcomes among women in HIV prevention
trials are urgently needed to inform use of effective antiretroviral agents for HIV prevention …

Uptake of hormonal contraceptives and correlates of uptake in a phase III clinical trial in rural South Western Uganda

A Abaasa, M Gafos, Z Anywaine, A Nunn, A Crook… - Reproductive health, 2017 - Springer
Background Use of a reliable contraception method has become an inclusion criterion in
prevention trials to minimize time off product. We report on hormonal contraceptive …

Pharmacokinetics of HIV therapies in pregnant patients: an update

M Neary, A Owen, A Olagunju - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction Mother-to-child transmission (MTCT) of HIV is thought to account for over 90%
of new pediatric infections, and is associated with poor maternal and fetal outcomes. As …

Use of reliable contraceptives and its correlates among women participating in simulated HIV vaccine efficacy trials in key-populations in Uganda

A Abaasa, J Todd, Y Mayanja, M Price, PE Fast… - Scientific reports, 2019 - nature.com
To prevent pregnancy in trials, reliable contraceptive use is key. We investigated reliable
contraceptive use at baseline and six months in key-populations in Uganda, during two …

Incidence and Predictors of Pregnancy in Women Enrolled in Large Multi-National HIV Treatment Trials of the AIDS Clinical Trials Group

AE Omoz-Oarhe, MD Hughes, Y Bao… - JAIDS Journal of …, 2022 - journals.lww.com
Objectives: Women are under-represented in clinical trials and must often commit to using
contraception to enroll. We sought to determine the incidence and predictors of pregnancy in …

Prevention of unintended pregnancy among female sex workers in low-and middle-income countries

F Ampt - bridges.monash.edu
Female sex workers in low-and middle-income countries are at high risk of unintended
pregnancy, but few programs address this issue. In addition, female sex workers rely heavily …