Antimicrobial resistance in bacteria: mechanisms, evolution, and persistence

E Christaki, M Marcou, A Tofarides - Journal of molecular evolution, 2020 - Springer
In recent years, we have seen antimicrobial resistance rapidly emerge at a global scale and
spread from one country to the other faster than previously thought. Superbugs and …

Targeting the holy triangle of quorum sensing, biofilm formation, and antibiotic resistance in pathogenic bacteria

RV Sionov, D Steinberg - Microorganisms, 2022 - mdpi.com
Chronic and recurrent bacterial infections are frequently associated with the formation of
biofilms on biotic or abiotic materials that are composed of mono-or multi-species cultures of …

Occurrence and Characteristics of Mobile Colistin Resistance (mcr) Gene-Containing Isolates from the Environment: A Review

MU Anyanwu, IF Jaja, OC Nwobi - International journal of environmental …, 2020 - mdpi.com
The emergence and spread of mobile colistin (COL) resistance (mcr) genes jeopardize the
efficacy of COL, a last resort antibiotic for treating deadly infections. COL has been used in …

Colistin resistance and management of drug resistant infections

J Sharma, D Sharma, A Singh… - Canadian Journal of …, 2022 - Wiley Online Library
Colistin resistance is a globalized sensible issue because it has been considered a drug of
the last‐line resort to treat drug‐resistant bacterial infections. The product of the mobilized …

Antimicrobial susceptibility testing for polymyxins: challenges, issues, and recommendations

F Ezadi, A Ardebili, R Mirnejad - Journal of clinical microbiology, 2019 - Am Soc Microbiol
Polymyxins, including polymyxin B and polymyxin E (colistin), are now increasingly being
used worldwide to treat patients with multidrug-resistant (MDR) Gram-negative bacterial …

Plasmid-mediated colistin resistance among human clinical Enterobacterales isolates: national surveillance in the Czech Republic

M Zelendova, CC Papagiannitsis, P Sismova… - Frontiers in …, 2023 - frontiersin.org
The occurrence of colistin resistance has increased rapidly among Enterobacterales around
the world. We performed a national survey of plasmid-mediated colistin resistance in human …

Global Distribution of mcr Gene Variants in 214K Metagenomic Samples

HM Martiny, P Munk, C Brinch, J Szarvas… - Msystems, 2022 - Am Soc Microbiol
Since the initial discovery of a mobilized colistin resistance gene (mcr-1), several other
variants have been reported, some of which might have circulated a while beforehand …

Pseudomonas aeruginosa Infections in Cancer Patients

P Paprocka, B Durnaś, A Mańkowska, G Król, T Wollny… - Pathogens, 2022 - mdpi.com
P seudomonas aeruginosa (P. aeruginosa) is one of the most frequent opportunistic
microorganisms causing infections in oncological patients, especially those with …

Prevalence of mobile colistin resistance (mcr) genes in extended-spectrum β-lactamase-producing Escherichia coli isolated from retail raw foods in Nha Trang …

PQ Le, SP Awasthi, N Hatanaka, A Hinenoya… - International Journal of …, 2021 - Elsevier
The aim of the study was to assess the presence of genes in ESBL-producing E. coli (ESBL-
Ec) isolated from retail raw food in Nha Trang, Vietnam. A total of 452 food samples …

Co-occurrence of mcr-1, mcr-3, mcr-7 and clinically relevant antimicrobial resistance genes in environmental and fecal samples

LDR Dos Santos, JPR Furlan, MS Ramos… - Archives of …, 2020 - Springer
Multidrug-resistant bacteria harboring different antimicrobial resistance genes (ARGs) have
been detected worldwide. The association of plasmid-mediated colistin resistance genes …