Genetics of rheumatoid arthritis

L Padyukov - Seminars in immunopathology, 2022 - Springer
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease involving symmetric joints
and is generally characterized by persistent pain, tenderness, and destruction of joints. The …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

Long noncoding RNAs and circular RNAs in autoimmune diseases

V Lodde, G Murgia, ER Simula, M Steri, M Floris… - Biomolecules, 2020 - mdpi.com
Immune responses are essential for the clearance of pathogens and the repair of injured
tissues; however, if these responses are not properly controlled, autoimmune diseases can …

Long non-coding RNAs and their “discrete” contribution to IBD and Johne's disease—what stands out in the current picture? A comprehensive review

KA Triantaphyllopoulos - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-coding RNAs (ncRNA) have paved the way to new perspectives on the regulation of
gene expression, not only in biology and medicine, but also in associated fields and …

Which long noncoding RNAs and circular RNAs contribute to inflammatory bowel disease?

L Lin, G Zhou, P Chen, Y Wang, J Han, M Chen… - Cell Death & …, 2020 - nature.com
Inflammatory bowel disease (IBD), a chronic relapsing gastrointestinal inflammatory
disease, mainly comprises ulcerative colitis (UC) and Crohn's disease (CD). Although the …

Dysregulation of lncRNAs in rheumatoid arthritis: biomarkers, pathogenesis and potential therapeutic targets

C Miao, L Bai, Y Yang, J Huang - Frontiers in pharmacology, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disease of unknown etiology, mainly
manifested by persistent abnormal proliferation of fibroblast-like synoviocytes (FLSs) …

[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations

D Kumar, SS Sahoo, D Chauss, M Kazemian… - Journal of …, 2023 - Elsevier
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …

Rheumatoid arthritis and non-coding RNAs; how to trigger inflammation

R Tofigh, M Hosseinpourfeizi, B Baradaran… - Life sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a systemic and chronic inflammatory disease categorized by
continuous synovitis in the joints and systemic inflammatory responses that can cause …

[HTML][HTML] Dysregulation of non-coding RNAs in rheumatoid arthritis

M Taheri, R Eghtedarian, ME Dinger… - Biomedicine & …, 2020 - Elsevier
Rheumatoid arthritis (RA) is a chronic inflammatory disorder that is associated with both
genetic and environmental factors. Dysregulation of the immune response is the main …

LncRNAs and rheumatoid arthritis: from identifying mechanisms to clinical investigation

W Huang, X Li, C Huang, Y Tang, Q Zhou… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic chronic autoinflammatory disease, and the synovial
hyperplasia, pannus formation, articular cartilage damage and bone matrix destruction …