[HTML][HTML] The impact of age on predictive performance of national early warning score at arrival to emergency departments: development and external validation

SK Nissen, BGJ Candel, CH Nickel, E de Jonge… - Annals of emergency …, 2022 - Elsevier
Study objective To investigate how age affects the predictive performance of the National
Early Warning Score (NEWS) at arrival to the emergency department (ED) regarding …

Assessing physiologic reserve and frailty in the older emergency department patient: should the paradigm change?

CH Nickel, J Kellett - Clinics in Geriatric Medicine, 2023 - geriatric.theclinics.com
Since 1990, patients aged 85 years and older have been the fastest growing segment of the
population. 1 Older adults are key service users of the emergency department (ED) …

Soluble urokinase plasminogen activator receptor: a biomarker for predicting complications and critical care admission of COVID-19 patients

A Chalkias, A Mouzarou, E Samara, T Xanthos… - Molecular Diagnosis & …, 2020 - Springer
The novel coronavirus infection has spread worldwide, causing a wide spectrum of clinical
manifestations. Most patients develop moderate clinical illness, but a substantial number will …

Circulating suPAR associates with severity and in‐hospital progression of COVID‐19

A Chalkias, A Skoulakis… - European journal of …, 2022 - Wiley Online Library
Background COVID‐19 disease progression is characterized by hyperinflammation and risk
stratification may aid in early aggressive treatment and advanced planning. The aim of this …

Decision-focused evaluation of worst-case distribution shift

K Ren, Y Byun, B Wilder - arXiv preprint arXiv:2407.03557, 2024 - arxiv.org
Distribution shift is a key challenge for predictive models in practice, creating the need to
identify potentially harmful shifts in advance of deployment. Existing work typically defines …

[HTML][HTML] Soluble urokinase plasminogen activator receptor (suPAR) in the emergency department: An update

D Velissaris, N Zareifopoulos… - Caspian Journal of …, 2022 - ncbi.nlm.nih.gov
Background: The biomarker soluble urokinase plasminogen activator receptor (suPAR) is an
indicator of inflammation which is increased in a variety of chronic and acute disease states …

Soluble urokinase plasminogen activator receptor level in individuals of advanced age

RN Wlazel, K Szwabe, A Guligowska, T Kostka - Scientific Reports, 2020 - nature.com
Soluble urokinase plasminogen activator receptor (suPAR) is a biomarker whose clinical
value has been tested in various groups of patients. The aim of the present study was to …

Pre-hospital suPAR, lactate and CRP measurements for decision-making: a prospective, observational study of patients presenting non-specific complaints

M Jousi, M Mäkinen, J Kaartinen, L Meriläinen… - Scandinavian Journal of …, 2021 - Springer
Background In the pre-hospital setting, non-urgent patients with non-specific chief
complaints pose assessment challenges for the emergency medical systems (EMS) …

Prevalence and clinical significance of point of care elevated lactate at emergency admission in older patients: a prospective study

M Gosselin, C Mabire, M Pasquier, PN Carron… - Internal and Emergency …, 2022 - Springer
Objective Patients who are over 65 years old represent up to 24% of emergency department
(ED) admissions. They are at increased risk of under-triage due to impaired physiological …

SEPSIGN: early identification of sepsis signs in emergency department

T Lafon, MA Cazalis, KW Hart, C Hennessy… - Internal and Emergency …, 2024 - Springer
Abstract Because 20-30% of patients with sepsis deteriorate to critical illness, biomarkers
that provide accurate early prognosis may identify which patients need more intensive …