RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Aberrant gene expression that drives human cancer can arise from epigenetic
dysregulation. Although much attention has focused on altered activity of transcription …

Abstract microRNAs (miRNAs) play critical roles in cancer development and progression.
This study investigated the effects of miR-138-5p in human colorectal cancer (CRC) …

MicroRNAs (miRNAs) represent an important class of small regulatory RNAs that control
gene expression posttranscriptionally by targeting mRNAs for degradation or translation …

Heart failure creates a leading public health burden worldwide and cardiac fibrosis is a
hallmark of pathological cardiac remodeling which was found in HF patients. In this study …

Cancer initiating/stem cells (CSCs) undergo self-renewal and differentiation that contributes
to tumor initiation, recurrence and metastasis in colorectal cancer (CRC). Targeting of …

Congestive heart failure (CHF) is a major cause of hospitalizations, morbidity, and mortality
in Western societies. In addition to optimal medical and device therapy, exercise training is …

Pediatric high-grade gliomas (pHGGs) are aggressive brain tumors affecting children, and
outcomes have remained dismal, even with access to new multimodal therapies. In this …

Cancer stem cells (CSCs) in colorectal tumorigenesis are suggested to be responsible for
initiation, development and propagation of colorectal cancer (CRC) and have been …

Colorectal cancer (CRC) is a major health problem with an estimated 1. 8 million new cases
worldwide. To date, most CRC studies have focused on DNA-related aberrations, leaving …