Background Gout is an inflammatory arthritis that is characterised by the deposition of
monosodium urate crystals in synovial fluid and other tissues. The natural history of articular …

Introduction Mediators of immunity and inflammation are playing a crucial role in COVID-19
pathogenesis and complications as demonstrated by several genetic and clinical studies …

Background: Gout is a common and debilitating condition that is associated with significant
morbidity and mortality. Despite advances in medical treatment, the global burden of gout …

Background Acute calcium pyrophosphate crystal arthritis causes intense joint pain mainly
affecting older people. Because guidance and evidence remain scarce, management of this …

Introduction Opioid analgesia for acute painful conditions has come under increasing
scrutiny with the public health crisis of opioid overdose, leading clinicians to seek nonopioid …

Background Gout is the most prevalent inflammatory arthritis in the Asia‐Pacific region and
worldwide. This clinical practice guideline (CPG) aims to provide recommendations based …

Pragmatic randomised clinical trials aim to directly inform clinical or health policy decision
making. Here, we systematically review methods and design of pragmatic trials of pain …

With a prevalence of 3.9% among all adults, and 9.7% in those older than 80, gout is the
most common inflammatory arthritis. 1 An analysis of National Health and Nutrition …

Colchicine is widely investigated for cardioprotection of COVID-19 patients since it can
prevent the phenomenon of 'cytokine storm'and may reduce the complications arising from …

Objective To develop a Gout, Hyperuricaemia and Crystal-Associated Disease Network (G-
CAN) common language definition of gout, with the goal of increasing public understanding …