Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology

CA Brosey, JA Tainer - Current opinion in structural biology, 2019 - Elsevier
Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …

In-depth analysis of biocatalysts by microfluidics: An emerging source of data for machine learning

M Vasina, D Kovar, J Damborsky, Y Ding, T Yang… - Biotechnology …, 2023 - Elsevier
Nowadays, the vastly increasing demand for novel biotechnological products is supported
by the continuous development of biocatalytic applications that provide sustainable green …

High-throughput in situ characterization of polymer crystallization under an intense flow, high pressure, and cooling gradient during injection molding

J Yin, LF Deng, GQ Ma, FY Wu, JZ Xu, X Gao… - …, 2023 - ACS Publications
Injection molding is a polymer-processing method widely used, which consumes about one-
third of global plastics and produces 80% of plastic parts. However, it is still challenging to in …

Tools for computational design and high-throughput screening of therapeutic enzymes

M Vasina, J Velecký, J Planas-Iglesias… - Advanced Drug Delivery …, 2022 - Elsevier
Therapeutic enzymes are valuable biopharmaceuticals in various biomedical applications.
They have been successfully applied for fibrinolysis, cancer treatment, enzyme replacement …

Microfluidic lab-on-chip advances for liquid–liquid extraction process studies

A Maurice, J Theisen, JCP Gabriel - Current Opinion in Colloid & Interface …, 2020 - Elsevier
The ever-increasing complexity of industrial product recycling calls for more efficient
purification processes such as liquid–liquid (L/L) extraction. Because of the high complexity …

Fundamentals to function: Quantitative and scalable approaches for measuring protein stability

B Atsavapranee, CD Stark, F Sunden, S Thompson… - Cell systems, 2021 - cell.com
Folding a linear chain of amino acids into a three-dimensional protein is a complex physical
process that ultimately confers an impressive range of diverse functions. Although recent …

Machine learning-driven, sensor-integrated microfluidic device for monitoring and control of supersaturation for automated screening of crystalline materials

P Coliaie, A Prajapati, R Ali, A Korde, MS Kelkar… - ACS …, 2022 - ACS Publications
Integrating sensors in miniaturized devices allow for fast and sensitive detection and precise
control of experimental conditions. One of the potential applications of a sensor-integrated …

Protein separation under a microfluidic regime

I Rodríguez-Ruiz, V Babenko, S Martínez-Rodríguez… - Analyst, 2018 - pubs.rsc.org
Lab-on-a-Chip (LoC), or micro-Total Analysis Systems (μTAS), is recognized as a powerful
analytical technology with high capabilities, though end-user products for protein purification …

An innovative data processing method for studying nanoparticle formation in droplet microfluidics using X-rays scattering

D Radajewski, L Hunter, X He, O Nahi, JM Galloway… - Lab on a Chip, 2021 - pubs.rsc.org
X-ray scattering techniques provide a powerful means of characterizing the formation of
nanoparticles in solution. Coupling these techniques to segmented-flow microfluidic devices …

OSTE+ for in situ SAXS analysis with droplet microfluidic devices

T Lange, S Charton, T Bizien, F Testard, F Malloggi - Lab on a Chip, 2020 - pubs.rsc.org
In recent years, microfluidic-based sample preparation techniques have emerged as a
powerful tool for measurements at large scale X-ray facilities. Most often the microfluidic …