Effect of DMARDs on the immunogenicity of vaccines

Y van Sleen, KSM van der Geest… - Nature Reviews …, 2023 - nature.com
Vaccines are important for protecting individuals at increased risk of severe infections,
including patients undergoing DMARD therapy. However, DMARD therapy can also …

Systemic sclerosis in the time of COVID-19

AM Hoffmann-Vold, O Distler, C Bruni… - The Lancet …, 2022 - thelancet.com
The COVID-19 pandemic represents one of the biggest challenges of the 21st century. In
addition to the general effect on society and health-care systems, patients with systemic …

[HTML][HTML] Booster dose of SARS-CoV-2 messenger RNA vaccines strengthens the specific immune response of patients with rheumatoid arthritis: A prospective …

C Farroni, A Aiello, A Picchianti-Diamanti… - International Journal of …, 2022 - Elsevier
Objectives To characterize the kinetics of humoral and T-cell responses in rheumatoid
arthritis (RA)-patients followed up to 4-6 weeks (T3) after the SARS-CoV-2 vaccine booster …

Optimal time for COVID-19 vaccination in rituximab-treated dermatologic patients

C Seree-Aphinan, Y Ratanapokasatit… - Frontiers in …, 2023 - frontiersin.org
Background By depleting circulating B lymphocytes, rituximab time-dependently suppresses
coronavirus disease 2019 (COVID-19) vaccines' humoral immunogenicity for a prolonged …

Pausing methotrexate prevents impairment of Omicron BA. 1 and BA. 2 neutralisation after COVID-19 booster vaccination

E Habermann, L Gieselmann, P Tober-Lau… - RMD open, 2022 - rmdopen.bmj.com
Objective The level of neutralising capacity against Omicron BA. 1 and BA. 2 after third
COVID-19 vaccination in patients on paused or continuous methotrexate (MTX) therapy is …

Safety and immunogenicity of a third COVID-19 vaccination in patients with immune-mediated inflammatory diseases compared with healthy controls

F Kartnig, D Mrak, E Simader, S Tobudic… - Annals of the …, 2023 - ard.bmj.com
Objectives A third COVID-19 vaccination is recommended for immunosuppressed patients.
However, data on immunogenicity and safety of a third COVID-19 vaccination in patients …

Microfluidic antibody profiling after repeated SARS-CoV-2 vaccination links antibody affinity and concentration to impaired immunity and variant escape in patients on …

A Priddey, MXH Chen-Xu, DJ Cooper… - Frontiers in …, 2024 - frontiersin.org
Background Patients with autoimmune/inflammatory conditions on anti-CD20 therapies,
such as rituximab, have suboptimal humoral responses to vaccination and are vulnerable to …

Analysis of the humoral and cellular response after the third COVID‐19 vaccination in patients with autoimmune hepatitis

J Hartl, DF Rüther, PM Duengelhoef… - Liver …, 2023 - Wiley Online Library
Background & aims To explore the humoral and T‐cell response to the third COVID‐19
vaccination in autoimmune hepatitis (AIH). Methods Anti‐SARS‐CoV‐2 antibody titers were …

Role of booster with BNT162b2 mRNA in SARS-CoV-2 vaccination in patients with rheumatoid arthritis

M Benucci, A Damiani, FL Gobbi, B Lari, V Grossi… - Immunologic …, 2022 - Springer
Only case reports and small clinical series report the effects of booster vaccination with
BNT162b2 in patients with rheumatoid arthritis (RA). We studied 200 patients with RA in …

Interaction of TNFi and conventional synthetic DMARD in SARS-CoV-2 vaccine response in axial spondyloarthritis and psoriatic arthritis

CGS Saad, MSR Silva, PD Sampaio-Barros… - Joint Bone Spine, 2023 - Elsevier
Objectives To evaluate humoral responses to three doses of the inactivated SARS-CoV-2
vaccine (CoronaVac) in patients with spondyloarthritis (SpA) and the effect of therapy …