Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders that affect the
skeletal muscles. Polymyositis, dermatomyositis, and inclusion body myositis are major IIM …

Biologic therapies targeting B-cells are emerging as an effective strategy to treat a variety of
immune-mediated diseases. One of the most studied B-cell-targeted therapies is rituximab …

There is no clear consensus in the literature regarding the choice of biologic therapies and
efficacy in juvenile dermatomyositis (JDM). In this review, we aimed to examine previous …

Introduction Dermatomyositis (DM) is a rare inflammatory disease with diverse cutaneous
and systemic manifestations, often associated with myositis-specific antibodies. Managing …

Abstract Cluster of differentiation 20 (CD20) is an integral membrane protein expressed
mainly on different developmental stages of B lymphocytes and rarely on T lymphocytes …

Abstract Purpose of Review Rituximab has transformed the treatment of B-cell malignancies
and rheumatoid arthritis in the past 2 decades. More recently, this anti-CD20 monoclonal …

Dermatomyositis is an autoimmune disease affecting both skin and muscle. Steroids are the
first line treatment. However, no consensus regarding dosing, length of treatment, tapering …

Intravenous immunoglobulin (IVIg) contains pooled immunoglobulins from the plasma of
healthy blood donors. All plasma samples are tested for HIV, hepatitis viruses (A, B, and C) …

Abstract Cluster of differentiation 20 (CD20) is an integral membrane protein expressed
mainly on different developmental stages of B lymphocytes and rarely on T lymphocytes …

A 66-year-old man with no past medical history, presented with an erythematous rash of the
face (Figure 1B), shoulders, and flanks associated with myalgia and proximal muscle …