Quantitative assessment of visceral obesity and postoperative colon cancer outcomes

OO Ozoya, EM Siegel, T Srikumar, AM Bloomer… - Journal of …, 2017 - Elsevier
Background Quantitative computed tomography (CT) assessment of visceral adiposity may
be superior to body mass index (BMI) as a predictor of surgical morbidity. We sought to …

Patient-derived interstitial fluids and predisposition to aggressive sporadic breast cancer through collagen remodeling and inactivation of p53

TC Kenny, H Schmidt, K Adelson, Y Hoshida… - Clinical cancer …, 2017 - AACR
Purpose: Despite the fact that interstitial fluid (IF) represents a third of our body fluid, it is the
most poorly understood body fluid in medicine. Increased IF pressure is thought to result …

Bioglass/ceria nanoparticle hybrids for the treatment of seroma: a comparative long-term study in rats

MA Pais, A Papanikolaou, IA Hoyos, R Nißler… - … in Bioengineering and …, 2024 - frontiersin.org
Background: Seroma formation is a common postoperative complication. Fibrin-based glues
are typically employed in an attempt to seal the cavity. Recently, the first nanoparticle (NP) …

Radiobiological effects of wound fluid on breast cancer cell lines and human-derived tumor spheroids in 2D and microfluidic culture

S Jeibouei, A Hojat, E Mostafavi, AR Aref, A Kalbasi… - Scientific Reports, 2022 - nature.com
Intraoperative radiotherapy (IORT) could abrogate cancer recurrences, but the underlying
mechanisms are unclear. To clarify the effects of IORT-induced wound fluid on tumor …

Transcriptomic and proteomic approaches reveal biological basis of intraoperative radiotherapy-treated tumor bed modification in breast cancer patients: A pilot study

M Shahani, J Shakeri, ME Akbari, B Arefnezhad… - Journal of …, 2020 - Elsevier
Abstract Aim Intraoperative electron Radiotherapy, herein referred to, as IOeRT is a novel
approach in breast cancer (BC) treatment. This study designed to investigate short-term …

Intraoperative radiation therapy induces immune response activity after pancreatic surgery

YS Lee, HS Kim, Y Cho, IJ Lee, HJ Kim, DE Lee… - BMC cancer, 2021 - Springer
Background Pancreatic cancer has highly aggressive features, such as local recurrence that
leads to significantly high morbidity and mortality and recurrence after successful tumour …

Computational mechanobiology model evaluating healing of postoperative cavities following breast-conserving surgery

Z Harbin, D Sohutskay, E Vanderlaan… - Computers in Biology …, 2023 - Elsevier
Breast cancer is the most commonly diagnosed cancer type worldwide. Given high
survivorship, increased focus has been placed on long-term treatment outcomes and patient …

Biological and clinical review of IORT-induced wound fluid in breast cancer patients

S Jeibouei, F Shams, F Mohebichamkhorami… - Frontiers in …, 2022 - frontiersin.org
Intraoperative radiotherapy (IORT) has become a growing therapy for early-stage breast
cancer (BC). Some studies claim that wound fluid (seroma), a common consequence of …

Wound fluid enhances cancer cell proliferation via activation of STAT3 signal pathway in vitro

A Scherzad, T Gehrke, T Meyer… - Oncology …, 2019 - spandidos-publications.com
Wound healing begins immediately after surgery with a modification of the
microenvironment via a well‑orchestrated interaction between cells, cytokines and growth …

[HTML][HTML] Dose-time and Source-Dependent Analysis of Intraoperative Radiotherapy-Treated Seroma on Breast Cancer Cell Types: A Pilot Study

M Shahani, J Shakeri, K Gilany, H Zali… - International Journal of …, 2022 - brieflands.com
Background: Intraoperative radiation therapy (IORT) is a novel approach to breast cancer
(BC) treatment. Objectives: In this study, we compared the cellular and molecular effects of …