Optimal influenza vaccine distribution with equity

S Enayati, OY Özaltın - European Journal of Operational Research, 2020 - Elsevier
This paper is concerned with the optimal influenza vaccine distribution in a heterogeneous
population consisting of multiple subgroups. We employ a compartmental model for …

Tightening piecewise McCormick relaxations for bilinear problems

PM Castro - Computers & Chemical Engineering, 2015 - Elsevier
We address nonconvex bilinear problems where the main objective is the computation of a
tight lower bound for the objective function to be minimized. This can be obtained through a …

Expanding scope and computational challenges in process scheduling

PM Castro, IE Grossmann, Q Zhang - Computers & Chemical Engineering, 2018 - Elsevier
In this paper, we present a brief overview of enterprise-wide optimization and challenges in
multiscale temporal modeling and integration of different models for the levels of planning …

Global optimization of bilinear programs with a multiparametric disaggregation technique

S Kolodziej, PM Castro, IE Grossmann - Journal of Global Optimization, 2013 - Springer
In this paper, we present the derivation of the multiparametric disaggregation technique
(MDT) by Teles et al.(J. Glob. Optim., 2011) for solving nonconvex bilinear programs. Both …

[图书][B] Methods and models in mathematical programming

SA MirHassani, F Hooshmand - 2019 - Springer
Operations research (OR) is a branch of mathematical sciences that aims to utilize
mathematical modeling, statistical analysis, and mathematical optimization systematically to …

A discretization-based approach for the optimization of the multiperiod blend scheduling problem

SP Kolodziej, IE Grossmann, KC Furman… - Computers & Chemical …, 2013 - Elsevier
In this paper, we introduce a new generalized multiperiod scheduling version of the pooling
problem to represent time varying blending systems. A general nonconvex MINLP …

Global optimal scheduling of crude oil blending operations with RTN continuous-time and multiparametric disaggregation

PM Castro, IE Grossmann - Industrial & Engineering Chemistry …, 2014 - ACS Publications
This paper addresses the modeling of crude oil operations in refineries assuming that all
properties blend linearly. Guidelines are given on how to generate a Resource-Task …

Normalized multiparametric disaggregation: an efficient relaxation for mixed-integer bilinear problems

PM Castro - Journal of Global Optimization, 2016 - Springer
A key element for the global optimization of non-convex mixed-integer bilinear problems is
the computation of a tight lower bound for the objective function being minimized …

[HTML][HTML] Assessment of a two-step approach for global optimization of mixed-integer polynomial programs using quadratic reformulation

T Karia, CS Adjiman, B Chachuat - Computers & Chemical Engineering, 2022 - Elsevier
This paper revisits the approach of transforming a mixed-integer polynomial program
(MIPOP) into a mixed-integer quadratically-constrained program (MIQCP), in the light of …

[HTML][HTML] Assessment of Lagrangean decomposition for short-term planning of integrated refinery-petrochemical operations

A Uribe-Rodríguez, PM Castro… - Computers & Chemical …, 2023 - Elsevier
We present an integrated methodology for optimal short-term planning of integrated refinery-
petrochemical complexes (IRPCs) and demonstrate it on a full-scale industrial case study …