Oestrogen receptor-α (ER) is the defining and driving transcription factor in the majority of
breast cancers and its target genes dictate cell growth and endocrine response, yet genomic …

The MEME Suite is a powerful, integrated set of web-based tools for studying sequence
motifs in proteins, DNA and RNA. Such motifs encode many biological functions, and their …

The first described feedback loop of the Arabidopsis circadian clock is based on reciprocal
regulation between TIMING OF CAB EXPRESSION 1 (TOC1) and CIRCADIAN CLOCK …

Adaptation to hypoxia is mediated through a coordinated transcriptional response driven
largely by hypoxia-inducible factor 1 (HIF-1). We used ChIP-chip and gene expression …

Breast cancer is a heterogeneous disease and several distinct subtypes exist based on
differential gene expression patterns. Molecular apocrine tumours were recently identified …

Up to 30% of the plant transcriptome is circadian clock‐regulated in different species;
however, we still lack a good understanding of the mechanisms involved in these genome …

Despite the large evolutionary distances between metazoan species, they can show
remarkable commonalities in their biology, and this has helped to establish fly and worm as …

Genes regulated by the same miRNA can be discovered by virtue of their coexpression at
the transcriptional level and the presence of a conserved miRNA-binding site in their 3 …

Gene expression is regulated in part by protein transcription factors that bind target
regulatory DNA sequences. Predicting DNA binding sites and affinities from transcription …

Background Simple sequence repeats (SSRs) are ubiquitous in eukaryotic genomes.
Chrysanthemum is one of the largest genera in the Asteraceae family. Only few …