Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

The intestinal tract of mammals is colonized by a large number of microorganisms including
trillions of bacteria that are referred to collectively as the gut microbiota. These indigenous …

Host microbial cross-talk is essential to maintain intestinal homeostasis. However,
maladaptation of this response through microbial dysbiosis or defective host defense toward …

The gut microbiota has diverse and essential roles in host metabolism, development of the
immune system and as resistance to pathogen colonization. Perturbations of the gut …

An effective resolution program may be able to prevent the progression from non-resolving
acute inflammation to persistent chronic inflammation. It has now become evident that …

Neutrophils and monocytes belong to the first line of immune defence cells and are recruited
to sites of inflammation during infection or sterile injury. Both cells contain huge amounts of …

Transition metals are required trace elements for all forms of life. Due to their unique
inorganic and redox properties, transition metals serve as cofactors for enzymes and other …

Transition metals occupy an essential niche in biological systems. Their electrostatic
properties stabilize substrates or reaction intermediates in the active sites of enzymes, and …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

Surface tissues of the body such as the skin and intestinal tract are in direct contact with the
external environment and are thus continuously exposed to large numbers of …