Cytosolic Ca 2+ concentration levels fluctuate in an ordered manner along the cell cycle, in
line with the fact that Ca 2+ is involved in the regulation of cell proliferation. Cell proliferation …

Salicylates from plant sources have been used for centuries by different cultures to treat a
variety of ailments such as inflammation, fever and pain. A chemical derivative of salicylic …

Evidence from a wide range of sources suggests that individuals taking aspirin and related
non-steroidal anti-inflammatory drugs have reduced risk of large bowel cancer. Work in …

Abstract Store-operated Ca 2+ entry (SOCE) is an important Ca 2+ influx pathway in many
non-excitable and some excitable cells. It is regulated by the filling state of intracellular Ca …

Cancer, the second cause of death worldwide, is characterized by several common criteria,
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …

Dysregulation of intracellular Ca2+ homeostasis may underlie amyloid β peptide (Aβ)
toxicity in Alzheimer's Disease (AD) but the mechanism is unknown. In search for this …

Abstract Background Toll-like receptors (TLRs) are transmembrane pattern-recognition
receptors of the innate immune system recognizing diverse pathogen-derived and tissue …

Background Endothelial progenitor cells (EPCs) may be recruited from bone marrow to
sustain tumor vascularisation and promote the metastatic switch. Understanding the …

The changes in intracellular free calcium (Ca2+) levels are one of the most widely regulators
of cell function; therefore, calcium as a universal intracellular mediator is involved in very …

Salicylic acid and related compounds are produced by plants as part of their defence
systems against pathogen attack and environmental stress. First identified in myrtle and …