Nuclear pore complexes are multiprotein channels that span the nuclear envelope, which
connects the nucleus to the cytoplasm. In addition to their main role in the regulation of …

Nuclear pore complex (NPC)-mediated nucleocytoplasmic trafficking is essential for key
cellular processes, such as cell growth, cell differentiation, and gene regulation. The NPC …

Mechanical signals from the extracellular microenvironment have been implicated in tumor
and metastatic progression. Here, we identify nucleoporin NUP210 as a metastasis …

Nuclear pore complexes (NPC) are the central mediators of nucleocytoplasmic transport.
Increasing evidence shows that many cancer cells have increased numbers of NPCs and …

Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) under androgen
deprivation therapy, by mechanisms eg expression of androgen receptor (AR) splice variant …

The nuclear pore complex (NPC) is a massive nuclear envelope-embedded protein
complex, the canonical function of which is to mediate selective nucleocytoplasmic transport …

Background and Aims Increasing evidence in recent years has suggested that microRNA‐7
(miR‐7) is an important gene implicated in the development of various diseases including …

Persistent androgen receptor (AR) signalling is the main driver of prostate cancer (PCa).
Truncated isoforms of the AR called androgen receptor variants (AR-Vs) lacking the ligand …

Nucleoporins (Nups) are involved in neural development, and alterations in Nup genes are
linked to human neurological diseases. However, physiological functions of specific Nups …

Nuclear import, mediated in part by karyopherin-α (KPNA)/importin-α subtypes, regulates
transcription factor access to the genome and determines cell fate. However, the cancer …