Background Poor retention of participants in randomised trials can lead to missing outcome
data which can introduce bias and reduce study power, affecting the generalisability, validity …

Introduction Alzheimer's disease (AD) pathology, including the accumulation of amyloid beta
(Aβ) species and tau pathology, begins decades before the onset of cognitive impairment …

The methods and results of health research are documented in study protocols, full study
reports (detailing all analyses), journal reports, and participant-level datasets. However …

Reproducibility, data sharing, personal data privacy concerns and patient enrolment in
clinical trials are huge medical challenges for contemporary clinical research. A new …

Background Chemoprevention of colorectal adenoma and colorectal cancer remains an
important public health goal. The present study aimed to investigate the clinical potential …

Objective To identify variations in outcomes and results across reports of randomized clinical
trials (RCTs). Study Design and Setting Eligible RCTs examined gabapentin for neuropathic …

Reporting guidelines for clinical trials evaluating artificial intelligence interventions are needed |
Nature Medicine Skip to main content Thank you for visiting nature.com. You are using a …

Clinical databases, particularly those composed of big data, face growing security
challenges. Blockchain, the open, decentralized, distributed public ledger technology …

Blockchain technology has shown tremendous attention towards a plethora of maximum
applications ranging from data management, financial services, IoT, food security, and …

Real-world research can use observational or clinical trial designs, in both cases putting
emphasis on high external validity, to complement the classical efficacy randomized …