On the evolution of variation in sexual reproduction through the prism of eukaryotic microbes

V Yadav, S Sun, J Heitman - Proceedings of the National …, 2023 - National Acad Sciences
Almost all eukaryotes undergo sexual reproduction to generate diversity and select for
fitness in their population pools. Interestingly, the systems by which sex is defined are highly …

Pentose metabolism and conversion to biofuels and high-value chemicals in yeasts

J Ruchala, AA Sibirny - FEMS Microbiology Reviews, 2021 - academic.oup.com
Pentose sugars are widespread in nature and two of them, D-xylose and L-arabinose
belong to the most abundant sugars being the second and third by abundance sugars in dry …

What makes Komagataella phaffii non-conventional?

Ö Ata, BG Ergün, P Fickers, L Heistinger… - FEMS Yeast …, 2021 - academic.oup.com
The important industrial protein production host Komagataella phaffii (syn Pichia pastoris) is
classified as a non-conventional yeast. But what exactly makes K. phaffii non-conventional …

Hansenula polymorpha methanol metabolism genes enhance recombinant protein production in Komagataella phaffi

M Khalifeh Soltani, S Arjmand, SO Ranaei Siadat… - AMB Express, 2024 - Springer
Recombinant protein production in Komagataella phaffi (K. phaffi), a widely utilized host
organism, can be optimized by enhancing the metabolic flux in the central carbon …

Mating-type switching in budding yeasts, from flip/flop inversion to cassette mechanisms

KH Wolfe, G Butler - Microbiology and Molecular Biology Reviews, 2022 - Am Soc Microbiol
Mating-type switching is a natural but unusual genetic control process that regulates cell
identity in ascomycete yeasts. It involves physically replacing one small piece of genomic …

Komagataella phaffii YPS1-5 encodes the alpha-factor degrading protease Bar1

L Heistinger, B Gasser, D Mattanovich - FEMS Yeast Research, 2020 - academic.oup.com
Yeast mating pheromones are small secreted peptides required for efficient mating between
cells of opposite mating type. Pheromone gradients allow the cells to detect potential mating …