Metabolomics Application in Maternal‐Fetal Medicine

V Fanos, L Atzori, K Makarenko… - BioMed research …, 2013 - Wiley Online Library
Metabolomics in maternal‐fetal medicine is still an “embryonic” science. However, there is
already an increasing interest in metabolome of normal and complicated pregnancies, and …

NMR metabolomics of human blood and urine in disease research

IF Duarte, SO Diaz, AM Gil - Journal of Pharmaceutical and Biomedical …, 2014 - Elsevier
This paper reviews the main applications of NMR metabolomics of blood and urine in
disease research, over the last 5 years. The broad range of disease types addressed attests …

Metabolomics of human amniotic fluid and maternal plasma during normal pregnancy

M Orczyk-Pawilowicz, E Jawien, S Deja, L Hirnle… - PloS one, 2016 - journals.plos.org
Metabolic profiles of amniotic fluid and maternal blood are sources of valuable information
about fetus development and can be potentially useful in diagnosis of pregnancy disorders …

Ketone body elevation in placenta, umbilical cord, newborn and mother in normal delivery

T Muneta, E Kawaguchi, Y Nagai… - Glycative Stress …, 2016 - jstage.jst.go.jp
1) Muneta Maternity Clinic, Ichihara, Chiba, Japan 2) Nagai Mothers Hospital, Misato,
Saitama, Japan 3) Takao Hospital, Kyoto, Japan 4) Osaka University Graduate School of …

Improving amino acid nutrition to prevent intrauterine growth restriction in mammals

G Lin, X Wang, G Wu, C Feng, H Zhou, D Li, J Wang - Amino acids, 2014 - Springer
Intrauterine growth restriction (IUGR) is one of the most common concerns in human
obstetrics and domestic animal production. It is usually caused by placental insufficiency …

Urinary metabolic profiles in early pregnancy are associated with preterm birth and fetal growth restriction in the Rhea mother–child cohort study

L Maitre, E Fthenou, T Athersuch, M Coen… - BMC medicine, 2014 - Springer
Background Preterm birth (PB) and fetal growth restriction (FGR) convey the highest risk of
perinatal mortality and morbidity, as well as increasing the chance of developing chronic …

Metabolomic profile of umbilical cord blood plasma from early and late intrauterine growth restricted (IUGR) neonates with and without signs of brain vasodilation

M Sanz-Cortés, RJ Carbajo, F Crispi, F Figueras… - PloS one, 2013 - journals.plos.org
Objectives To characterize via NMR spectroscopy the full spectrum of metabolic changes in
umbilical vein blood plasma of newborns diagnosed with different clinical forms of …

Second trimester maternal urine for the diagnosis of trisomy 21 and prediction of poor pregnancy outcomes

SO Diaz, AS Barros, BJ Goodfellow… - Journal of proteome …, 2013 - ACS Publications
Given the recognized lack of prenatal clinical methods for the early diagnosis of preterm
delivery, intrauterine growth restriction, preeclampsia and gestational diabetes mellitus, and …

Metabolomics tools for describing complex pesticide exposure in pregnant women in Brittany (France)

N Bonvallot, M Tremblay-Franco, C Chevrier, C Canlet… - PloS one, 2013 - journals.plos.org
Background The use of pesticides and the related environmental contaminations can lead to
human exposure to various molecules. In early-life, such exposures could be responsible for …

Cord blood metabolic signatures of birth weight: a population-based study

O Robinson, P Keski-Rahkonen, L Chatzi… - Journal of proteome …, 2018 - ACS Publications
Birth weight is an important indicator of maternal and fetal health and a predictor of health in
later life. However, the determinants of variance in birth weight are still poorly understood …