Communicating clocks shape circadian homeostasis

KB Koronowski, P Sassone-Corsi - Science, 2021 - science.org
BACKGROUND Life-forms ranging from bacteria to humans are programmed by circadian
clocks—mechanisms that impose an~ 24-hour rhythmicity on biology in harmony with …

Chrono‐nutrition: from molecular and neuronal mechanisms to human epidemiology and timed feeding patterns

A Flanagan, DA Bechtold, GK Pot… - Journal of …, 2021 - Wiley Online Library
The circadian timing system governs daily biological rhythms, synchronising physiology and
behaviour to the temporal world. External time cues, including the light‐dark cycle and …

[HTML][HTML] Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer's disease

DS Whittaker, L Akhmetova, D Carlin, H Romero… - Cell metabolism, 2023 - cell.com
Circadian disruptions impact nearly all people with Alzheimer's disease (AD), emphasizing
both their potential role in pathology and the critical need to investigate the therapeutic …

The physiological control of eating: signals, neurons, and networks

AG Watts, SE Kanoski, G Sanchez-Watts… - Physiological …, 2022 - journals.physiology.org
During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

New insights into the circadian rhythm and its related diseases

Y Xie, Q Tang, G Chen, M Xie, S Yu, J Zhao… - Frontiers in …, 2019 - frontiersin.org
Circadian rhythms (CR) are a series of endogenous autonomous oscillators generated by
the molecular circadian clock which acting on coordinating internal time with the external …

Central and peripheral circadian clocks in mammals

JA Mohawk, CB Green… - Annual review of …, 2012 - annualreviews.org
The circadian system of mammals is composed of a hierarchy of oscillators that function at
the cellular, tissue, and systems levels. A common molecular mechanism underlies the cell …

The mammalian circadian clock and its entrainment by stress and exercise

Y Tahara, S Aoyama, S Shibata - The Journal of Physiological Sciences, 2017 - Springer
The mammalian circadian clock regulates day–night fluctuations in various physiological
processes. The circadian clock consists of the central clock in the suprachiasmatic nucleus …

Circadian rhythms in the hypothalamo–pituitary–adrenal (HPA) axis

A Kalsbeek, R Van der Spek, J Lei, E Endert… - Molecular and cellular …, 2012 - Elsevier
The pronounced daily variation in the release of adrenal hormones has been at the heart of
the deciphering and understanding of the circadian timing system. Indeed, the first …

Mechanisms of communication in the mammalian circadian timing system

M Astiz, I Heyde, H Oster - International journal of molecular sciences, 2019 - mdpi.com
24-h rhythms in physiology and behaviour are organized by a body-wide network of
endogenous circadian clocks. In mammals, a central pacemaker in the hypothalamic …

[HTML][HTML] Molecular profiling of activated neurons by phosphorylated ribosome capture

ZA Knight, K Tan, K Birsoy, S Schmidt, JL Garrison… - Cell, 2012 - cell.com
The mammalian brain is composed of thousands of interacting neural cell types. Systematic
approaches to establish the molecular identity of functional populations of neurons would …