Role of pncA gene mutations W68R and W68G in pyrazinamide resistance
Mycobacterium tuberculosis (Mtb) resistance toward anti‐tuberculosis drugs is a widespread
problem. Pyrazinamide (PZA) is a first line antitubercular drug that kills semi‐dormant bacilli …
problem. Pyrazinamide (PZA) is a first line antitubercular drug that kills semi‐dormant bacilli …
Differential expression profiles of long noncoding RNAs and mRNAs in human bone marrow mesenchymal stem cells after exposure to a high dosage of …
T Li, Y Xu, Y Wang, Y Jiang - Stem cell research & therapy, 2021 - Springer
Background Abnormalities in apoptosis, cell cycle, proliferation, and differentiation of human
bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and …
bone marrow mesenchymal stem cells (hBMSCs) significantly impact bone metabolism and …
Proteomics analysis of tangeretin-induced apoptosis through mitochondrial dysfunction in bladder cancer cells
JJ Lin, CC Huang, YL Su, HL Luo, NL Lee… - International Journal of …, 2019 - mdpi.com
Tangeretin is one of the most abundant compounds in citrus peel, and studies have shown
that it possesses anti-oxidant and anti-cancer properties. However, no study has been …
that it possesses anti-oxidant and anti-cancer properties. However, no study has been …
Analysis of the binding sites on BAX and the mechanism of BAX activators through extensive molecular dynamics simulations
The BAX protein is a pro-apoptotic member of the Bcl-2 family, which triggers apoptosis by
causing permeabilization of the mitochondrial outer membrane. However, the activation …
causing permeabilization of the mitochondrial outer membrane. However, the activation …
Wild-type catalase peroxidase vs G279D mutant type: Molecular basis of Isoniazid drug resistance in Mycobacterium tuberculosis
Mycobacterium tuberculosis katG gene is responsible for production of an enzyme catalase
peroxidase that peroxidises and activates the prodrug Isoniazid (INH), a first-line …
peroxidase that peroxidises and activates the prodrug Isoniazid (INH), a first-line …
Structural investigations on mechanism of lapatinib resistance caused by HER-2 mutants
HER-2 belongs to the human epidermal growth factor receptor (HER) family. Via different
signal transduction pathways, HER-2 regulates normal cell proliferation, survival, and …
signal transduction pathways, HER-2 regulates normal cell proliferation, survival, and …
Double Mutants in DNA Gyrase Lead to Ofloxacin Resistance in Mycobacterium tuberculosis
Fluoroquinolones are among the most important classes of highly effective antibacterial
drugs, exhibiting wide range of activity to cure infectious diseases. Ofloxacin is second …
drugs, exhibiting wide range of activity to cure infectious diseases. Ofloxacin is second …
Insight into the inhibitor discrimination by FLT 3 F691L
Fms‐like tyrosine kinase 3 (FLT 3) belongs to the receptor tyrosine kinase family and
expressed in hematopoietic progenitor cells. FLT 3 gene mutations are reported in~ 30% of …
expressed in hematopoietic progenitor cells. FLT 3 gene mutations are reported in~ 30% of …
Dissecting the role of mutations in chymase inhibition: free energy and decomposition analysis
Chymase enzyme abundantly found in secretory granules of mast cells and catalyzes the
hydrolysis of peptide bonds to generate angiotensin II via hydrolysis of angiotensin I and …
hydrolysis of peptide bonds to generate angiotensin II via hydrolysis of angiotensin I and …
[PDF][PDF] Differential Expression Pro les of Long Noncoding RNA and mRNA in Dexamethasone-Induced Apoptosis of Human Bone Marrow Mesenchymal Stem Cells
T Li, Y Xu, Y Wang, Y Jiang - scholar.archive.org
Background Abnormalities in apoptosis, cell cycle, and proliferation of human bone marrow
mesenchymal stem cells (hBMSCs) signi cantly impact bone metabolism and remodeling …
mesenchymal stem cells (hBMSCs) signi cantly impact bone metabolism and remodeling …