Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light

H Serrage, V Heiskanen, WM Palin… - Photochemical & …, 2019 - pubs.rsc.org
Photobiomodulation (PBM) describes the application of light at wavelengths ranging from
400–1100 nm to promote tissue healing, reduce inflammation and promote analgesia …

An expanding role for nonvisual opsins in extraocular light sensing physiology

M Andrabi, BA Upton, RA Lang… - Annual Review of Vision …, 2023 - annualreviews.org
We live on a planet that is bathed in daily and seasonal sunlight cycles. In this context,
terrestrial life forms have evolved mechanisms that directly harness light energy (plants) or …

Accelerated burn wound healing with photobiomodulation therapy involves activation of endogenous latent TGF-β1

I Khan, SU Rahman, E Tang, K Engel, B Hall… - Scientific reports, 2021 - nature.com
The severity of tissue injury in burn wounds from associated inflammatory and immune
sequelae presents a significant clinical management challenge. Among various biophysical …

Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor

RN Ozdeslik, LE Olinski, MM Trieu… - Proceedings of the …, 2019 - National Acad Sciences
Opsins form a family of light-activated, retinal-dependent, G protein-coupled receptors
(GPCRs) that serve a multitude of visual and nonvisual functions. Opsin 3 (OPN3 or …

Olfactory, taste, and photo sensory receptors in non-sensory organs: it just makes sense

NM Dalesio, SF Barreto Ortiz, JL Pluznick… - Frontiers in …, 2018 - frontiersin.org
Sensory receptors that detect and respond to light, taste, and smell primarily belong to the G-
protein-coupled receptor (GPCR) superfamily. In addition to their established roles in the …

Does blue light restore human epidermal barrier function via activation of Opsin during cutaneous wound healing?

I Castellano‐Pellicena… - Lasers in surgery …, 2019 - Wiley Online Library
Background and Objective Visible light has beneficial effects on cutaneous wound healing,
but the role of potential photoreceptors in human skin is unknown. In addition, inconsistency …

Photobiomodulation with blue light on wound healing: a scoping review

TP Prado, FC Zanchetta, B Barbieri, C Aparecido… - Life, 2023 - mdpi.com
Background: Photobiomodulation consists of inducing healing by irradiating light. This
scoping review investigates the effect of blue light on the healing process. Methods: The …

Adaptive thermogenesis in mice is enhanced by opsin 3-dependent adipocyte light sensing

G Nayak, KX Zhang, S Vemaraju, Y Odaka, ED Buhr… - Cell reports, 2020 - cell.com
Almost all life forms can detect and decode light information for adaptive advantage.
Examples include the visual system, in which photoreceptor signals are processed into …

Opsins outside the eye and the skin: a more complex scenario than originally thought for a classical light sensor

MN Moraes, LVM de Assis, I Provencio… - Cell and Tissue …, 2021 - Springer
Since the discovery of melanopsin as a retinal non-visual photopigment, opsins have been
described in several organs and cells. This distribution is strikingly different from the …

Steering the multipotent mesenchymal cells towards an anti-inflammatory and osteogenic bias via photobiomodulation therapy: How to kill two birds with one stone

A Amaroli, C Pasquale, A Zekiy… - Journal of Tissue …, 2022 - journals.sagepub.com
The bone marrow-derived multipotent mesenchymal cells (MSCs) have captured scientific
interest due to their multi-purpose features and clinical applications. The operational …