Role of Nrf2 signaling cascade in breast cancer: strategies and treatment

H Kumar, RM Kumar, D Bhattacharjee… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the second leading cancer among all types of cancers. It accounts for 12%
of the total cases of cancers. The complex and heterogeneous nature of breast cancer …

Synergies in exosomes and autophagy pathways for cellular homeostasis and metastasis of tumor cells

L Salimi, A Akbari, N Jabbari, B Mojarad, A Vahhabi… - Cell & Bioscience, 2020 - Springer
Background Eukaryotic cells demonstrate two tightly linked vesicular transport systems,
comprising intracellular vesicle transport and extracellular vesicle transport system …

The Egr-1/miR-15a-5p/GPX4 axis regulates ferroptosis in acute myocardial infarction

K Fan, W Huang, H Qi, C Song, C He, Y Liu… - European journal of …, 2021 - Elsevier
Acute myocardial infarction (AMI) is a type of cardiovascular diseases that severely
threatens human being, but the mechanisms have not been thoroughly clarified. Here, we …

m7G methyltransferase METTL1 promotes post-ischemic angiogenesis via promoting VEGFA mRNA translation

Y Zhao, L Kong, Z Pei, F Li, C Li, X Sun… - Frontiers in cell and …, 2021 - frontiersin.org
Post-transcriptional modifications play pivotal roles in various pathological processes and
ischemic disorders. However, the role of N7-methylguanosine (m7G), particularly m7G in …

Crosstalk between macrophages and cardiac cells after myocardial infarction

Y Jian, X Zhou, W Shan, C Chen, W Ge, J Cui… - Cell Communication and …, 2023 - Springer
Cardiovascular diseases, such as myocardial infarction (MI), are a leading cause of death
worldwide. Acute MI (AMI) inflicts massive injury to the coronary microcirculation, causing …

Angiogenesis-on-a-chip coupled with single-cell RNA sequencing reveals spatially differential activations of autophagy along angiogenic sprouts

S Lee, H Kim, BS Kim, S Chae, S Jung, JS Lee… - Nature …, 2024 - nature.com
Several functions of autophagy associated with proliferation, differentiation, and migration of
endothelial cells have been reported. Due to lack of models recapitulating angiogenic …

Hypoxia, oxidative stress, and immune evasion: a trinity of the trichothecenes T-2 toxin and deoxynivalenol (DON)

L You, Y Zhao, K Kuca, X Wang, P Oleksak… - Archives of …, 2021 - Springer
T-2 toxin and deoxynivalenol (DON) are type A and B trichothecenes, respectively. They
widely occur as pollutants in food and crops and cause a series of toxicities, including …

Targeting autophagy in prostate cancer: preclinical and clinical evidence for therapeutic response

M Ashrafizadeh, MDA Paskeh, S Mirzaei… - Journal of Experimental …, 2022 - Springer
Prostate cancer is a leading cause of death worldwide and new estimates revealed prostate
cancer as the leading cause of death in men in 2021. Therefore, new strategies are pertinent …

Diagnostic and prognostic biomarkers for myocardial infarction

Y Wu, N Pan, Y An, M Xu, L Tan… - Frontiers in cardiovascular …, 2021 - frontiersin.org
The incidence of myocardial infarction (MI) increases every year worldwide. Better
diagnostic and prognostic biomarkers for clinical applications are the consistent pursuit of MI …

Keap1‐Nrf2 signaling pathway in angiogenesis and vascular diseases

Z Guo, Z Mo - Journal of Tissue Engineering and Regenerative …, 2020 - Wiley Online Library
The transcription factor, nuclear factor E2‐related factor 2 (Nrf2), is highly sensitive to
oxidative burst products, including reactive oxygen species (ROS) and reactive nitrogen …