Diffuse low-grade glioma grows, migrates along white matter tracts, and progresses to high-
grade glioma. Rather than a “wait and see” policy, an aggressive attitude is now …

Abstract Purpose of Review Low-grade gliomas (LGG) are a group of primary brain tumors
that arise from supporting glial cells. They are characterized by a mutation in the isocitrate …

The finding that most grades II and III gliomas harbor isocitrate dehydrogenase (IDH)
mutations conveying a relatively favorable and fairly similar prognosis in both tumor grades …

Background Awake surgery with intraoperative electrical mapping emerged as a gold-
standard approach in newly diagnosed diffuse low-grade glioma (DLGG) to optimize the …

Simple Summary Diffuse low-grade gliomas (LGG) are relatively uncommon primary brain
cancers. In recent years, the molecular, diagnostic, and therapeutic approaches have …

Background Surgical resection and irradiation of diffuse glioma are guided by standard MRI:
T2/fluid attenuated inversion recovery (FLAIR)–weighted MRI for non-enhancing and T1 …

Simple Summary Brain tumors comprise a large, varied group, with gliomas being the most
common malignant tumors arising in the brain. This state-of-the-art review discusses the role …

The management of diffuse supratentorial WHO grade II glioma remains a challenge
because of the infiltrative nature of the tumor, which precludes curative therapy after total or …

Purpose: Isocitrate dehydrogenase–mutant (IDH-mt) gliomas are incurable primary brain
tumors characterized by a slow-growing phase over several years followed by a rapid …

Gliomas represent the majority of malignant central nervous system tumors, with the most
aggressive subtype, glioblastoma, accounting for almost 57% of this entity. Type of glioma …