HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination

C Evans, CE Jones, AJ Prendergast - The Lancet infectious diseases, 2016 - thelancet.com
The number of infants infected with HIV is declining with the rise in interventions for the
elimination of paediatric HIV infection, but the number of uninfected infants exposed to HIV …

The role of environmental factors in modulating immune responses in early life

DM MacGillivray, TR Kollmann - Frontiers in immunology, 2014 - frontiersin.org
The concept of immunological memory stipulates that past exposures shape present
immune function. These exposures include not only specific antigens impacting adaptive …

Congenital cytomegalovirus infection burden and epidemiologic risk factors in countries with universal screening: a systematic review and meta-analysis

P Ssentongo, C Hehnly, P Birungi, MA Roach… - JAMA network …, 2021 - jamanetwork.com
Importance Congenital cytomegalovirus (cCMV) infection is the most common congenital
infection and the leading acquired cause of developmental disabilities and sensorineural …

COVID‐19 in pregnancy: Placental and neonatal involvement

E Prochaska, M Jang, I Burd - American journal of reproductive …, 2020 - Wiley Online Library
Since December 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2)
has caused over 12 million infections and more than 550 000 deaths. 1 Morbidity and …

Growth and neurodevelopment of HIV-exposed uninfected children: a conceptual framework

CJ Wedderburn, C Evans, S Yeung, DM Gibb… - Current HIV/AIDS …, 2019 - Springer
Abstract Purpose of Review The population of HIV-exposed uninfected (HEU) children is
expanding rapidly, and over one million HEU infants are born each year globally. Several …

Pattern of infectious morbidity in HIV-exposed uninfected infants and children

AL Slogrove, T Goetghebuer, MF Cotton… - Frontiers in …, 2016 - frontiersin.org
Background Almost 30% of children in Southern Africa are HIV exposed but uninfected
(HEU) and experience exposures that could increase vulnerability to infectious diseases …

A meta-analysis assessing all-cause mortality in HIV-exposed uninfected compared with HIV-unexposed uninfected infants and children

AT Brennan, R Bonawitz, CJ Gill, DM Thea… - Aids, 2016 - journals.lww.com
Objective: Conduct a meta-analysis examining differential all-cause mortality rates between
HIV-exposed uninfected (HEU) infants and children as compared with their HIV-unexposed …

Fc characteristics mediate selective placental transfer of IgG in HIV-infected women

DR Martinez, Y Fong, SH Li, F Yang, MF Jennewein… - Cell, 2019 - cell.com
The placental transfer of maternal IgG is critical for infant protection against infectious
pathogens. However, factors that modulate the placental transfer of IgG remain largely …

The immune system of HIV-exposed uninfected infants

B Abu-Raya, TR Kollmann, A Marchant… - Frontiers in …, 2016 - frontiersin.org
Infants born to human immunodeficiency virus (HIV) infected women are HIV-exposed but
the majority remains uninfected [ie, HIV-exposed uninfected (HEU)]. HEU infants suffer …

Epidemiology of acute lower respiratory tract infection in HIV-exposed uninfected infants

C Cohen, J Moyes, S Tempia, M Groome… - …, 2016 - publications.aap.org
BACKGROUND: Increased morbidity and mortality from lower respiratory tract infection
(LRTI) has been suggested in HIV-exposed uninfected (HEU) children; however, the …