The intestinal epithelium must balance efficient absorption of nutrients with partitioning
commensals and pathogens from the bodies' largest immune system. If this crucial barrier …

Pheochromocytoma and paraganglioma (PPGL) require prompt consideration and efficient
diagnosis and treatment to minimize associated morbidity and mortality. Once considered …

Deep sequencing of the gut microbiomes of 1135 participants from a Dutch population-
based cohort shows relations between the microbiome and 126 exogenous and intrinsic …

Abstract Background Neuroendocrine tumors (NETs) are a form of cancer that differ from
other neoplasia in that they synthesize, store, and secrete peptides, eg, chromogranin A …

The chromogranins (chromogranin A and chromogranin B), secretogranins (secretogranin II
and secretogranin III), and additional related proteins (7B2, NESP55, proSAAS, and VGF) …

The pathogenesis of ulcerative colitis (UC), a major type of inflammatory bowel disease,
remains unknown. No model exists that adequately recapitulates the complexity of clinical …

Owing to the heterogeneity of neuroendocrine neoplasms (NENs), the availability of reliable
circulating markers is critical for improving diagnostics, prognostic stratification, follow-up …

The acute phase of IBD with inflamed gut and often ulcerated mucosa is clearly different
from the apparently normal mucosa characteristic of IBS. However, more detailed …

Gut inflammation is characterized by mucosal recruitment of activated cells from both the
innate and adaptive immune systems. In addition to immune cells, inflammation in the gut is …

An accurate tumor marker is a critical tool in tumor management because it establishes an
uncertain diagnosis, offers a basis for individual prognostication, signals response to …