The inhibitor of kappa B kinase (IKK) family consists of IKKα, IKKβ, and the IKK-related
kinases TBK1 and IKKε. These kinases are considered master regulators of inflammation …

Diabetic nephropathy (DN) leads to high morbidity and disability. Inflammation plays a
critical role in the pathogenesis of DN, which involves renal cells and immune cells, the …

Helicobacter pylori is a pathogen that colonizes the stomach and causes chronic gastritis.
Helicobacter pylori can colonize deep inside gastric glands, triggering increased R‐spondin …

The IκB kinase (IKK)‐NF‐κB pathway is activated as part of the DNA damage response and
controls both inflammation and resistance to apoptosis. How these distinct functions are …

Exposure to ultrafine particulate matter (PM0. 1) is positively associated with the etiology of
different acute and chronic disorders; however, the in-depth biological imprints that link …

The 5′-terminal cap is a fundamental determinant of eukaryotic gene expression which
facilitates cap-dependent translation and protects mRNAs from exonucleolytic degradation …

Immune sentinel cells initiate immune responses to pathogens and tissue injury and are
capable of producing highly stimulus-specific responses. Insight into the mechanisms …

In a genome‐wide screening for components of the dsDNA‐break‐induced IKK‐NF‐κB
pathway, we identified scores of regulators, including tumor susceptibility gene TSG101 …

Activation of the transcription factor NF-κB elicits an individually tailored transcriptional
response in order to meet the particular requirements of specific cell types, tissues, or …

Simple Summary Gene expression regulated by the NF-κB transcription factor pathway is a
multi-step process that finally results in the synthesis of proteins, many of which are …