Chemical aspects of human and environmental overload with fluorine

J Han, L Kiss, H Mei, AM Remete… - Chemical …, 2021 - ACS Publications
Over the last 100–120 years, due to the ever-increasing importance of fluorine-containing
compounds in modern technology and daily life, the explosive development of the …

Review on PLGA polymer based nanoparticles with antimicrobial properties and their application in various medical conditions or infections

AK Shakya, M Al-Sulaibi, RR Naik, H Nsairat, S Suboh… - Polymers, 2023 - mdpi.com
The rise in the resistance to antibiotics is due to their inappropriate use and the use of a
broad spectrum of antibiotics. This has also contributed to the development of multidrug …

Assessing drug-induced mitochondrial toxicity in cardiomyocytes: implications for preclinical cardiac safety evaluation

X Tang, Z Wang, S Hu, B Zhou - Pharmaceutics, 2022 - mdpi.com
Drug-induced cardiotoxicity not only leads to the attrition of drugs during development, but
also contributes to the high morbidity and mortality rates of cardiovascular diseases …

Platensimycin-Encapsulated Poly(lactic-co-glycolic acid) and Poly(amidoamine) Dendrimers Nanoparticles with Enhanced Anti-Staphylococcal Activity in Vivo

X Liu, Z Wang, X Feng, E Bai, Y Xiong, X Zhu… - Bioconjugate …, 2020 - ACS Publications
Serious bacterial infections by multi-drug-resistant pathogens lead to human losses and
endanger public health. The discovery of antibiotics with new modes of action, in …

Photoexcited triclosan induced DNA damage and oxidative stress via p38 MAP kinase signaling involving type I radicals under sunlight/UVB exposure

D Dubey, AK Srivastav, J Singh, D Chopra… - Ecotoxicology and …, 2019 - Elsevier
Triclosan (TCS) is an antimicrobial preservative used in personal care products. Here, we
have studied the phototoxicity, photogenotoxicity of TCS and its molecular mechanism …

Fabrication of polymeric sorafenib coated chitosan and fucoidan nanoparticles: Investigation of anticancer activity and apoptosis in colorectal cancer cells

Y Zhou, J Liu, S Ma, X Yang, Z Zou, W Lu, T Wang… - Heliyon, 2024 - cell.com
The most prevalent form of colon cancer also ranks high among cancer-related deaths
globally. Traditional chemotherapy drugs do not provide sufficient therapeutic efficacy, and …

Anti-ESBL derivatives of marine endophytic Streptomyces xiamenensis GRG 5 (KY457709) against ESBL producing bacteria

G Rajivgandhi, G Ramachandran, R Vijayan… - New Journal of …, 2022 - pubs.rsc.org
The emerging threat of extended spectrum beta lactamase (ESBL) producing Gram negative
bacteria still remains an important worldwide concern. Due to insufficient drug choice and …

Preparation and Characterization of Polymeric Microparticles Based on Poly (ethylene brassylate-co-squaric Acid) Loaded with Norfloxacin

AM Șerban, I Nacu, I Rosca, A Ghilan, AG Rusu… - Pharmaceutics, 2024 - mdpi.com
In recent years, increasing interest has been accorded to polyester-based polymer
microstructures, driven by their promising potential as advanced drug delivery systems. This …

A convergent synthetic platform of hydrogels enclosing prednisolone-loaded nanoparticles for the treatment of chronic actinic dermatitis

Q Chen, H Deng, B Liang, R Li, H Li, Y Ke… - Materials …, 2023 - Taylor & Francis
Recurrent eczematous lesions and acute itching describe chronic actinic dermatitis (CAD).
Continuous use of corticosteroids might result in a dermal adverse effect. Chitosan (CS) …

A First Report of Docosahexaenoic Acid‐Clocked Polymer Enveloped Gold Nanoparticles: A Way to Precision Breast Cancer and Triple Negative Breast Cancer …

L Khanna, S Ballal, KK Awasthi, D Singh… - Journal of Applied …, 2024 - Wiley Online Library
Functionalized gold nanoparticles (GNPs) are extensively utilized in various disciplines due
to their excellent bioactivity, biocompatibility, and extended drug half‐life, influenced by the …