Potassium channels: Novel targets for tumor diagnosis and chemoresistance

M Li, P Tian, Q Zhao, X Ma, Y Zhang - Frontiers in Oncology, 2023 - frontiersin.org
In recent years, the role of potassium channels in tumors has been intensively studied.
Potassium channel proteins are widely involved in various physiological and pathological …

[HTML][HTML] Potassium channels, tumorigenesis and targeted drugs

C Xia, C Liu, S Ren, Y Cai, Q Zhang, C Xia - Biomedicine & …, 2023 - Elsevier
Potassium channels play an important role in human physiological function. Recently,
various molecular mechanisms have implicated abnormal functioning of potassium …

A potent ion channel blocker, hydroquinidine, exhibits strong anti-cancer activity on colon, pancreatic, and hepatocellular cancer cells

M Yavuz, T Demircan - Molecular Biology Reports, 2023 - Springer
Background Despite recent advances in drug discovery, cancer is still one of the most lethal
health problems worldwide. In most cases, standard therapy methods and multi-modal …

[HTML][HTML] Immunosuppressive effects of new thiophene-based KV1. 3 inhibitors

Š Gubič, A Montalbano, C Sala, A Becchetti… - European journal of …, 2023 - Elsevier
Voltage-gated potassium channel KV 1.3 inhibitors have been shown to be effective in
preventing T-cell proliferation and activation by affecting intracellular Ca 2+ homeostasis …

[HTML][HTML] Insight into a multifunctional potassium channel Kv1. 3 and its novel implication in chronic kidney disease

Z Dragan, CA Pollock, C Huang - Life Sciences, 2024 - Elsevier
Chronic kidney disease (CKD), a global public health problem, causes substantial morbidity
and mortality worldwide. Innovative therapeutic strategies to mitigate the progression of CKD …

Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14, 2595

Š Gubič, LA Hendrickx, X Shi, Ž Toplak, Š Možina… - Cancers, 2023 - mdpi.com
Cancers | Free Full-Text | Correction: Gubič et al. Design of New Potent and Selective
Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14 …

[HTML][HTML] The 'Patch-Clamp'Technique and its Application in Studies on Voltage-Gated Potassium Channels Kv1. 3 in Normal and Cancer Cells

A Teisseyre, K Środa-Pomianek, A Palko-Labuz - 2024 - intechopen.com
The introduction of this chapter presents a historical outline of experimental methods applied
in electrophysiology until development of the 'patch-clamp'technique. The first section briefly …

Acute and delayed drug effects on voltage-gated potassium channels= Acute en vertraagde geneesmiddel effecten op spanningsgevoelige kaliumkanalen

K Van Theemsche - 2024 - repository.uantwerpen.be
The voltage-dependent K⁺(Kv) channel family is large compared to other ion channel
families, owing to a diverse array of genes encoding different α-subunits. In some …

[图书][B] Voltage-Gated Potassium Channels Kv1. 3 in Health and Disease

A Teisseyre, K Środa-Pomianek, A Palko-Labuz… - 2023 - intechopen.com
Voltage-gated potassium channels Kv1. 3 are widely expressed among many cell types,
both in the plasma membrane and in the inner mitochondrial membrane (mito Kv1. 3 …

[PDF][PDF] Correction: Gubic et al. Design of New Potent and Selective Thiophene-Based KV1. 3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14 …

Š Gubic, LA Hendrickx, X Shi, Ž Toplak, Š Možina… - 2023 - lirias.kuleuven.be
Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors
and Their Potential for Anticancer Page 1 Citation: Gubic, Š.; Hendrickx, LA; Shi, X.; Toplak, Ž.; …