C Xia, C Liu, S Ren, Y Cai, Q Zhang, C Xia - Biomedicine & …, 2023 - Elsevier
Potassium channels play an important role in human physiological function. Recently, various molecular mechanisms have implicated abnormal functioning of potassium …
Background Despite recent advances in drug discovery, cancer is still one of the most lethal health problems worldwide. In most cases, standard therapy methods and multi-modal …
Š Gubič, A Montalbano, C Sala, A Becchetti… - European journal of …, 2023 - Elsevier
Voltage-gated potassium channel KV 1.3 inhibitors have been shown to be effective in preventing T-cell proliferation and activation by affecting intracellular Ca 2+ homeostasis …
Z Dragan, CA Pollock, C Huang - Life Sciences, 2024 - Elsevier
Chronic kidney disease (CKD), a global public health problem, causes substantial morbidity and mortality worldwide. Innovative therapeutic strategies to mitigate the progression of CKD …
Š Gubič, LA Hendrickx, X Shi, Ž Toplak, Š Možina… - Cancers, 2023 - mdpi.com
Cancers | Free Full-Text | Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Activity. Cancers 2022, 14 …
A Teisseyre, K Środa-Pomianek, A Palko-Labuz - 2024 - intechopen.com
The introduction of this chapter presents a historical outline of experimental methods applied in electrophysiology until development of the 'patch-clamp'technique. The first section briefly …
The voltage-dependent K⁺(Kv) channel family is large compared to other ion channel families, owing to a diverse array of genes encoding different α-subunits. In some …
A Teisseyre, K Środa-Pomianek, A Palko-Labuz… - 2023 - intechopen.com
Voltage-gated potassium channels Kv1. 3 are widely expressed among many cell types, both in the plasma membrane and in the inner mitochondrial membrane (mito Kv1. 3 …
Š Gubic, LA Hendrickx, X Shi, Ž Toplak, Š Možina… - 2023 - lirias.kuleuven.be
Correction: Gubič et al. Design of New Potent and Selective Thiophene-Based KV1.3 Inhibitors and Their Potential for Anticancer Page 1 Citation: Gubic, Š.; Hendrickx, LA; Shi, X.; Toplak, Ž.; …