S Mostert, A Petzer, JP Petzer - ChemMedChem, 2015 - Wiley Online Library
Recent reports document that α‐tetralone (3, 4‐dihydro‐2H‐naphthalen‐1‐one) is an appropriate scaffold for the design of high‐potency monoamine oxidase (MAO) inhibitors …
Abstract Series of structurally diverse 2-imidazoline derivatives have been synthesized by condensation of substituted aldehydes with ethylenediamine, Pd-catalyzed N-arylation of 2 …
Studies have shown that natural and synthetic chalcones (1, 3-diphenyl-2-propen-1-ones) possess monoamine oxidase (MAO) inhibition activities. Of particular importance to the …
C De Monte, S Carradori, P Chimenti, D Secci… - European journal of …, 2014 - Elsevier
Although there are clinical trials and in vivo studies in literature regarding the anxiolytic and antidepressant activities of the components of Crocus sativus L., their effects on the human …
U Salgin-Goksen, G Telli, A Erikci… - Journal of medicinal …, 2021 - ACS Publications
Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3, 5- disubstitutedphenyl-2-pyrazoline structure and nine compounds having N′-(1, 3 …
In the present study, a series of fifteen α-tetralone (3, 4-dihydro-2H-naphthalen-1-one) derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine …
In the present study, a series of twenty-two 2-benzylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) …
Monoamine oxidases (MAOs) are key metabolic enzymes for neurotransmitter and dietary amines and are targets for the treatment of neuropsychiatric and neurodegenerative …
In the present study a series of fifteen 2-heteroarylidene-1-indanone derivatives were synthesised and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) …